Journal
BIOSENSORS & BIOELECTRONICS
Volume 77, Issue -, Pages 249-263Publisher
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2015.09.038
Keywords
Biosensor; Chemosensor; Cellulose paper; Paper microfluidics; Lateral flow assays
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Funding
- University of Minnesota MnDRIVE Global Food Venture
- USDA National Institute of Food and Agriculture [1006789]
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Remarkable efforts have been dedicated to paper-based chemosensors and biosensors over the last few years, mainly driven by the promise of reaching the best trade-off between performance, affordability and simplicity. Because of the low-cost and rapid prototyping of these sensors, recent research has been focused on providing affordable diagnostic devices to the developing world. The recent progress in sensitivity, multi-functionality and integration of microfluidic paper-based analytical devices (mu PADs), increasingly suggests that this technology is not only attractive in resource-limited environments but it also represents a serious challenger to silicon, glass and polymer-based biosensors. This review discusses the design, chemistry and engineering aspects of these developments, with a focus on the past few years. (C) 2015 Elsevier B.V. All rights reserved.
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