Journal
SENSORS
Volume 19, Issue 21, Pages -Publisher
MDPI
DOI: 10.3390/s19214619
Keywords
microfluidics; nanomolar nitrite; in situ marine sensor; lab-on-chip; valve
Funding
- Natural Sciences and Engineering Research Council (NSERC) Canada
- Ocean Frontier Institute (OFI)
- Marine Environmental Observation Prediction and Response Network (MEOPAR)
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Presented here is the fabrication and characterization of a tunable microfluidic check valve for use in marine nutrient sensing. The ball-style valve makes use of a rare-earth permanent magnet, which exerts a pulling force to ensure it remains passively sealed until the prescribed cracking pressure is met. By adjusting the position of the magnet, the cracking pressure is shown to be customizable to meet design requirements. Further applicability is shown by integrating the valve into a poly(methyl methacrylate) (PMMA) lab-on-chip device with an integrated optical absorbance cell for nitrite detection in seawater. Micro-milling is used to manufacture both the valve and the micro-channel structures. The valve is characterized up to a flow rate of 14 mL min(-1) and exhibits low leakage rates at high back pressures (<2 mu L min(-1) at similar to 350 kPa). It is low cost, requires no power, and is easily implemented on microfluidic platforms.
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