4.8 Article

Effective seed-assisted synthesis of gold nanoparticles anchored nitrogen-doped graphene for electrochemical detection of glucose and dopamine

Journal

BIOSENSORS & BIOELECTRONICS
Volume 81, Issue -, Pages 259-267

Publisher

ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2016.02.070

Keywords

Gold nanoparticles; N-doped graphene; Electrocatalysis; Non-enzymatic glucose sensor; Dopamine sensor

Funding

  1. Basic Research Laboratory Program through Ministry of Science, ICT & Future Planning [2014R1A4A1008140]
  2. Basic Science Research Program through National Research Foundation (NRF) - Ministry of Education of Korea [2013R1A1A2011608]
  3. National Research Foundation of Korea [2014R1A4A1008140, 2013R1A1A2011608] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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A novel gold nanoparticle-anchored nitrogen-doped graphene (AuNP/NG) nanohybrid was synthesized through a seed-assisted growth method, as an effective electrocatalyst for glucose and dopamine detection. The AuNP/NG nanohybrids exhibited high sensitivity and selectivity toward glucose and dopamine sensing applications. The as-synthesized nanohybrids exhibited excellent catalytic activity toward glucose, with a linear response throughout the concentration range from 40 mu M to 16.1 mM, a detection limit of 12 mu M, and a short response time (similar to 10 s ). It also exhibited an excellent response toward DA, with a wide detection range from 30 nM to 48 mu M, a low detection limit of 10 nM, and a short response time (similar to 8 s). Furthermore, it also showed long-term stability and high selectivity for the target analytes. These results imply that such nanohybrids show a great potential for electrochemical biosensing application. (C) 2016 Elsevier B.V. All rights reserved.

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