Journal
BIOSENSORS & BIOELECTRONICS
Volume 86, Issue -, Pages 899-906Publisher
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2016.07.091
Keywords
ECL immunosensor; CdTe QDs; Au nanoparticles; ZnO nanorods; Poly(amidoamine)-graphene; Brombuterol
Categories
Funding
- Science Fund from the National Natural Science Foundation of China [21075087, 21175097]
- Project of Scientific and Technologic Infrastructure of Suzhou [SZS201207]
- Priority Academic Program Development of Jiangsu Higher Education Institution [YX10900212]
Ask authors/readers for more resources
beta-adrenergic agonists (beta-agonists) recognized as a growth promoter will reflect the health of human. Sensitive detection of (beta-agonists in foodstuff is valuable for the health of animals and human. A novel ultrasensitive competition-type electrochemiluminescent (ECL) immunosensor was developed for detecting brombuterol (Brom) based on CdTe Quantum dot (QDs) and polyamidoamine dendrimer (PAMAM, G2) modified graphene oxide (GO) (CdTe QDs-PAMAM-GO composite) as bioprobe for the first time. The surface of glassy carbon electrode (GCE) was coated with AuNPs-ZnO NRs composite film as the platform, which facilitated the electronic transmission rate to enhance the ECL intensity and provide enough active sites for capturing antibody. The resulting ECL immunosensor enabled the real samples detection of Brom with a lower detection limit of 0.3 pg mL(-1) (S/N=3) and a wider linear range from 0.001 to 500 ng mL(-1). The proposed immunosensor coupled with the excellent advantages of CdTe QDs-PAMAM-GO and AuNPs-ZnO NRs composite displayed high sensitivity and long-term stability, and provided an approach for determining other important biomarkers. (C) 2016 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available