Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 80, Issue 9, Pages 1700-1711Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/09168451.2016.1177446
Keywords
Aspergillus species; cell wall; polysaccharides; signal transduction; glucans
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Funding
- Japan Society for the Promotion of Science [KAKENHI] [15K07348]
- Grants-in-Aid for Scientific Research [26292037, 15K07348] Funding Source: KAKEN
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Aspergillus species are among the most important filamentous fungi from the viewpoints of industry, pathogenesis, and mycotoxin production. Fungal cells are exposed to a variety of environmental stimuli, including changes in osmolality, temperature, and pH, which create stresses that primarily act on fungal cell walls. In addition, fungal cell walls are the first interactions with host cells in either human or plants. Thus, understanding cell wall structure and the mechanism of their biogenesis is important for the industrial, medical, and agricultural fields. Here, we provide a systematic review of fungal cell wall structure and recent findings regarding the cell wall integrity signaling pathways in aspergilli. This accumulated knowledge will be useful for understanding and improving the use of industrial aspergilli fermentation processes as well as treatments for some fungal infections.
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