4.4 Article

The isoflavone fraction from soybean presents mRNA maturation inhibition activity

Journal

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 81, Issue 3, Pages 551-554

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/09168451.2016.1249451

Keywords

Soyaflavone HG; luciferase; RNA-FISH

Funding

  1. Central Miso Research Institute
  2. Skylark Food Science Institute
  3. Fuji Foundation for Protein Research
  4. Takano Life Science Research Foundation
  5. Asahi Group Foundation
  6. Tojuro Iijima Foundation for Food Science and Technology
  7. Foundation for Dietary Scientific Research
  8. JSBBA Innovative Research Program Award
  9. JSPS Kakenhi [15K11299]
  10. Grants-in-Aid for Scientific Research [26870309, 15H04501, 17K19232, 15K11299] Funding Source: KAKEN

Ask authors/readers for more resources

Recent findings indicate that mRNA splicing inhibitors can be potential anticancer candidates. We have previously established a screening system which monitors mRNA processing in order to identify mRNA processing inhibitors. Among a number of dietary resources, isoflavone fractions showed an inhibitory effect of mRNA processing. These findings demonstrate that a variety of dietary sources have an impact on mRNA biogenesis.

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