Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 80, Issue 11, Pages 2165-2167Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/09168451.2016.1206808
Keywords
ginsenoside Re; cornified cell envelope; filaggrin; caspase-14; HaCaT
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Funding
- Korean Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea [HN12C0060]
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Ginsenoside Re (Re), a major ginsenoside of ginseng, enhanced the cornified cell envelope (CE) formation in HaCaT keratinocytes under normal conditions. In HaCaT keratinocytes, Re was also able to upregulate filaggrin protein and caspase-14 activity in a concentration-dependent manner. These findings reasonably imply that Re possesses a desirable property of improving skin barrier function.
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