Related references
Note: Only part of the references are listed.Increased Muscleblind levels by chloroquine treatment improve myotonic dystrophy type 1 phenotypes in in vitro and in vivo models
Ariadna Bargiela et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion
Mario Mauthe et al.
AUTOPHAGY (2018)
Correction of GSK3β at young age prevents muscle pathology in mice with myotonic dystrophy type 1
Christina Wei et al.
FASEB JOURNAL (2018)
Metformin induces autophagy and G0/G1 phase cell cycle arrest in myeloma by targeting the AMPK/mTORC1 and mTORC2 pathways
Yan Wang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models
Estefania Cerro-Herreros et al.
NATURE COMMUNICATIONS (2018)
Improved mobility with metformin in patients with myotonic dystrophy type 1: a randomized controlled trial
Guillaume Bassez et al.
BRAIN (2018)
RNA-mediated therapies in myotonic dystrophy
Sarah J. Overby et al.
DRUG DISCOVERY TODAY (2018)
A flow cytometry-based screen identifies MBNL1 modulators that rescue splicing defects in myotonic dystrophy type
Fan Zhang et al.
HUMAN MOLECULAR GENETICS (2017)
Reduced cytoplasmic MBNL1 is an early event in a brain-specific mouse model of myotonic dystrophy
Pei-Ying Wang et al.
HUMAN MOLECULAR GENETICS (2017)
Targeting deregulated AMPK/mTORC1 pathways improves muscle function in myotonic dystrophy type I
Marielle Brockhoff et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Myotonic dystrophy: disease repeat range, penetrance, age of onset, and relationship between repeat size and phenotypes
Kevin Yum et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2017)
Immortalized human myotonic dystrophy muscle cell lines to assess therapeutic compounds
Ludovic Arandel et al.
DISEASE MODELS & MECHANISMS (2017)
Identification of Plant-derived Alkaloids with Therapeutic Potential for Myotonic Dystrophy Type I
Ruben Herrendorff et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Derepressing muscleblind expression by miRNA sponges ameliorates myotonic dystrophy-like phenotypes in Drosophila
Estefania Cerro-Herreros et al.
SCIENTIFIC REPORTS (2016)
Dose-Dependent Regulation of Alternative Splicing by MBNL Proteins Reveals Biomarkers for Myotonic Dystrophy
Stacey D. Wagner et al.
PLOS GENETICS (2016)
Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy
Guiying Chen et al.
SCIENTIFIC REPORTS (2016)
Differential Scanning Fluorimetry for Monitoring RNA Stability
Robert Silvers et al.
CHEMBIOCHEM (2015)
Increased autophagy and apoptosis contribute to muscle atrophy in a myotonic dystrophy type 1 Drosophila model
Ariadna Bargiela et al.
DISEASE MODELS & MECHANISMS (2015)
Essential role for autophagy in life span extension
Frank Madeo et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin
Delphine Laustriat et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2015)
o Clinical Potential of microRNA-7 in Cancer
Jessica L. Horsham et al.
JOURNAL OF CLINICAL MEDICINE (2015)
Loss of MBNL Leads to Disruption of Developmentally Regulated Alternative Polyadenylation in RNA-Mediated Disease
Ranjan Batra et al.
MOLECULAR CELL (2014)
Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models
Hyung-Jun Kim et al.
NATURE GENETICS (2014)
Two Enhancers Control Transcription of Drosophila muscleblind in the Embryonic Somatic Musculature and in the Central Nervous System
Ariadna Bargiela et al.
PLOS ONE (2014)
Splicing Biomarkers of Disease Severity in Myotonic Dystrophy
Masayuki Nakamori et al.
ANNALS OF NEUROLOGY (2013)
Muscleblind, BSF and TBPH are mislocalized in the muscle sarcomere of a Drosophila myotonic dystrophy model
Beatriz Llamusi et al.
DISEASE MODELS & MECHANISMS (2013)
Novel Drosophila model of myotonic dystrophy type 1: phenotypic characterization and genome-wide view of altered gene expression
Lucie Picchio et al.
HUMAN MOLECULAR GENETICS (2013)
RNA Interference Targeting CUG Repeats in a Mouse Model of Myotonic Dystrophy
Krzysztof Sobczak et al.
MOLECULAR THERAPY (2013)
Overexpression of CUGBP1 in Skeletal Muscle from Adult Classic Myotonic Dystrophy Type 1 but Not from Myotonic Dystrophy Type 2
Rosanna Cardani et al.
PLOS ONE (2013)
Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins
Eric T. Wang et al.
CELL (2012)
Mouse model of muscleblind-like 1 overexpression: skeletal muscle effects and therapeutic promise
Christopher M. Chamberlain et al.
HUMAN MOLECULAR GENETICS (2012)
GSK3β mediates muscle pathology in myotonic dystrophy
Karlie Jones et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Muscleblind-like 2-Mediated Alternative Splicing in the Developing Brain and Dysregulation in Myotonic Dystrophy
Konstantinos Charizanis et al.
NEURON (2012)
CUGBP1 and MBNL1 preferentially bind to 3′ UTRs and facilitate mRNA decay
Akio Masuda et al.
SCIENTIFIC REPORTS (2012)
THERAPEUTICS DEVELOPMENT IN MYOTONIC DYSTROPHY TYPE 1
Erin Pennock Foff et al.
MUSCLE & NERVE (2011)
Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy
Charlotte Fugier et al.
NATURE MEDICINE (2011)
Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy
Frederique Rau et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Normal myogenesis and increased apoptosis in myotonic dystrophy type-1 muscle cells
E. Loro et al.
CELL DEATH AND DIFFERENTIATION (2010)
Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1
Misha Koshelev et al.
HUMAN MOLECULAR GENETICS (2010)
Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy
Hongqing Du et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Global regulation of alternative splicing during myogenic differentiation
Christopher S. Bland et al.
NUCLEIC ACIDS RESEARCH (2010)
A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart
Auinash Kalsotra et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy
Rahul N. Kanadia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy
Xiaoyan Lin et al.
HUMAN MOLECULAR GENETICS (2006)
Mammalian CELF/Bruno-like RNA-binding proteins:: molecular characteristics and biological functions
Carine Barreau et al.
BIOCHIMIE (2006)
RNA leaching of transcription factors disrupts transcription in myotonic dystrophy
A Ebralidze et al.
SCIENCE (2004)
Histopathological differences of myotonic dystrophy type 1 (DM1) and PROMM/DM2
A Vihola et al.
NEUROLOGY (2003)
Loss of the muscle-specific chloride channel in type 1 myotonic dystrophy due to misregulated alternative splicing
N Charlet-B et al.
MOLECULAR CELL (2002)
Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy
RS Savkur et al.
NATURE GENETICS (2001)
Alternative exon-encoded regions of Drosophila myosin heavy chain modulate ATPase rates and actin sliding velocity
DM Swank et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat
A Mankodi et al.
SCIENCE (2000)