Related references
Note: Only part of the references are listed.Clinical Phenotypes of Carriers of Mutations in CHD8 or Its Conserved Target Genes
Jennifer S. Beighley et al.
BIOLOGICAL PSYCHIATRY (2020)
Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions
Summer B. Thyme et al.
CELL (2019)
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons
Kirill Zaslaysky et al.
NATURE NEUROSCIENCE (2019)
Habituation Learning Is a Widely Affected Mechanism in Drosophila Models of Intellectual Disability and Autism Spectrum Disorders
Michaels Fenckova et al.
BIOLOGICAL PSYCHIATRY (2019)
Distributed Plasticity Drives Visual Habituation Learning in Larval Zebrafish
Owen Randlett et al.
CURRENT BIOLOGY (2019)
Intellectual disability and autism spectrum disorders 'on the fly': insights from Drosophila
Mireia Coll-Tane et al.
DISEASE MODELS & MECHANISMS (2019)
CNTN5-/+ or EHMT2-/+ human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks
Eric Deneault et al.
ELIFE (2019)
Habituation Is More Than Learning to Ignore: Multiple Mechanisms Serve to Facilitate Shifts in Behavioral Strategy
Troy A. McDiarmid et al.
BIOESSAYS (2019)
VariCarta: A Comprehensive Database of Harmonized Genomic Variants Found in Autism Spectrum Disorder Sequencing Studies
Manuel Belmadani et al.
AUTISM RESEARCH (2019)
CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in Caenorhabditis elegans
Vinci Au et al.
G3-GENES GENOMES GENETICS (2019)
Male-specific deficits in natural reward learning in a mouse model of neurodevelopmental disorders
N. M. Grissom et al.
MOLECULAR PSYCHIATRY (2018)
Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum
Andrea Ganna et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2018)
Beyond the response-High throughput behavioral analyses to link genome to phenome in Caenorhabditis elegans
T. A. McDiarmid et al.
GENES BRAIN AND BEHAVIOR (2018)
Abnormal mTOR Activation in Autism
Kellen D. Winden et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 41 (2018)
Ethology as a physical science
Andre E. X. Brown et al.
NATURE PHYSICS (2018)
Wnt/β-catenin signaling stimulates the expression and synaptic clustering of the autism-associated Neuroligin 3 gene
Matias A. Medina et al.
TRANSLATIONAL PSYCHIATRY (2018)
Neurexin controls plasticity of a mature, sexually dimorphic neuron
Michael P. Hart et al.
NATURE (2018)
An open-source platform for analyzing and sharing worm-behavior data
Avelino Javer et al.
NATURE METHODS (2018)
DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers
Shanshan Li et al.
NUCLEIC ACIDS RESEARCH (2018)
Role of VTA dopamine neurons and neuroligin 3 in sociability traits related to nonfamiliar conspecific interaction
Sebastiano Bariselli et al.
NATURE COMMUNICATIONS (2018)
Large-scale investigation of the reasons why potentially important genes are ignored
Thomas Stoeger et al.
PLOS BIOLOGY (2018)
CRISPR-Cas9 human gene replacement and phenomic characterization in Caenorhabditis elegans to understand the functional conservation of human genes and decipher variants of uncertain significance
Troy A. McDiarmid et al.
DISEASE MODELS & MECHANISMS (2018)
Building Models of Brain Disorders with Three-Dimensional Organoids
Neal D. Amin et al.
NEURON (2018)
Insights into the roles of CMK-1 and OGT-1 in interstimulus interval-dependent habituation in Caenorhabditis elegans
Evan L. Ardiel et al.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2018)
Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons
Eric Deneault et al.
STEM CELL REPORTS (2018)
OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes
Woojin Kim et al.
GENETICS (2018)
Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism
M. Jiang et al.
MOLECULAR PSYCHIATRY (2017)
Model Organisms Facilitate Rare Disease Diagnosis and Therapeutic Research
Michael F. Wangler et al.
GENETICS (2017)
Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases
Holly A. F. Stessman et al.
NATURE GENETICS (2017)
Retrograde Synaptic Inhibition Is Mediated by α-Neurexin Binding to the α2δ Subunits of N-Type Calcium Channels
Xia-Jing Tong et al.
NEURON (2017)
Sensory processing in autism spectrum disorders and Fragile X syndrome-From the clinic to animal models
D. Sinclair et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2017)
Habituation is altered in neuropsychiatric disorders-A comprehensive review with recommendations for experimental design and analysis
Troy A. McDiarmid et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2017)
Deep evolutionary conservation of autism-related genes
Hagai Y. Shpigler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Functional significance of rare neuroligin 1 variants found in autism
Moe Nakanishi et al.
PLOS GENETICS (2017)
Model Organisms Facilitate Rare Disease Diagnosis and Therapeutic Research
Michael F. Wangler et al.
GENETICS (2017)
Variant Interpretation: Functional Assays to the Rescue
Lea M. Starita et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2017)
Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor trafficking
S. Chanda et al.
MOLECULAR PSYCHIATRY (2016)
Systematic Phenomics Analysis Deconvolutes Genes Mutated in Intellectual Disability into Biologically Coherent Modules
Korinna Kochinke et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs
Lauren L. Orefice et al.
CELL (2016)
An extended set of yeast-based functional assays accurately identifies human disease mutations
Song Sun et al.
GENOME RESEARCH (2016)
Advancing the understanding of autism disease mechanisms through genetics
Luis de la Torre-Ubieta et al.
NATURE MEDICINE (2016)
Deep phenotyping unveils hidden traits and genetic relations in subtle mutants
Adriana San-Miguel et al.
NATURE COMMUNICATIONS (2016)
The auxin-inducible degradation (AID) system enables versatile conditional protein depletion in C-elegans
Liangyu Zhang et al.
DEVELOPMENT (2015)
Conditional neuroligin-2 knockout in adult medial prefrontal cortex links chronic changes in synaptic inhibition to cognitive impairments
J. Liang et al.
MOLECULAR PSYCHIATRY (2015)
Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci
Stephan J. Sanders et al.
NEURON (2015)
Autism-associated mutation inhibits protein kinase C-mediated neuroligin-4X enhancement of excitatory synapses
Michael A. Bemben et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism
Olga Penagarikano et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Mutations and Modeling of the Chromatin Remodeler CHD8 Define an Emerging Autism Etiology
Rebecca A. Barnard et al.
FRONTIERS IN NEUROSCIENCE (2015)
Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity
J. Ellegood et al.
MOLECULAR PSYCHIATRY (2015)
A Genotype-First Approach to Defining the Subtypes of a Complex Disease
Holly A. Stessman et al.
CELL (2014)
Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development
Raphael Bernier et al.
CELL (2014)
Synaptic, transcriptional and chromatin genes disrupted in autism
Silvia De Rubeis et al.
NATURE (2014)
The contribution of de novo coding mutations to autism spectrum disorder
Ivan Iossifov et al.
NATURE (2014)
Drosophila models of early onset cognitive disorders and their clinical applications
Monique van der Voet et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2014)
Transgene-Free Genome Editing in Caenorhabditis elegans Using CRISPR-Cas
Hui Chiu et al.
GENETICS (2013)
A database of Caenorhabditis elegans behavioral phenotypes
Eviatar Yemini et al.
NATURE METHODS (2013)
A dictionary of behavioral motifs reveals clusters of genes affecting Caenorhabditis elegans locomotion
Andre E. X. Brown et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Systematic profiling of Caenorhabditis elegans locomotive behaviors reveals additional components in G-protein Gαq signaling
Hui Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
Brian J. O'Roak et al.
NATURE (2012)
Functional Phenotypic Rescue of Caenorhabditis elegans Neuroligin-Deficient Mutants by the Human and Rat NLGN1 Genes
Fernando Calahorro et al.
PLOS ONE (2012)
Shared Synaptic Pathophysiology in Syndromic and Nonsyndromic Rodent Models of Autism
Stephane J. Baudouin et al.
SCIENCE (2012)
Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities
Huda Y. Zoghbi et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
A High-Resolution C. elegans Essential Gene Network Based on Phenotypic Profiling of a Complex Tissue
Rebecca A. Green et al.
CELL (2011)
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
Pascal S. Kaeser et al.
CELL (2011)
Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
Sergiu P. Pasca et al.
NATURE MEDICINE (2011)
High-throughput behavioral analysis in C. elegans
Nicholas A. Swierczek et al.
NATURE METHODS (2011)
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
Mark Etherton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Adult Neural Function Requires MeCP2
Christopher M. McGraw et al.
SCIENCE (2011)
Behavioural phenotyping assays for mouse models of autism
Jill L. Silverman et al.
NATURE REVIEWS NEUROSCIENCE (2010)
CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis
Masaaki Nishiyama et al.
NATURE CELL BIOLOGY (2009)
Minimal Aberrant Behavioral Phenotypes of Neuroligin-3 R451C Knockin Mice
Kathryn K. Chadman et al.
AUTISM RESEARCH (2008)
Neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice
Katsuhiko Tabuchi et al.
SCIENCE (2007)
Reversal of neurological defects in a mouse model of Rett syndrome
Jacky Guy et al.
SCIENCE (2007)
Pten regulates neuronal arborization and social interaction in mice
Chang-Hyuk Kwon et al.
NEURON (2006)
Finding function in novel targets:: C-elegans as a model organism
T Kaletta et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Systematic analysis of genes required for synapse structure and function
D Sieburth et al.
NATURE (2005)
A novel β-catenin-binding protein inhibits β-catenin-dependent Tcf activation and axis formation
I Sakamoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
