Journal
PHYTOCHEMISTRY
Volume 166, Issue -, Pages -Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2019.112063
Keywords
Chlorogenic acids; Lignin; Phenylpropanoids; Shikimate; Quinate; Hydroxycinnamoyl CoA:shikimate/quinate hydroxycinnamoyl transferase; Caffeoyl shikimate esterase
Categories
Funding
- Sao Paulo Research Foundation for a doctoral fellowship (Processo FAPESP) [2014/17831-5]
- Brazilian National Council for Scientific and Technological Development (CNPq)
- FAPESP for the BIOEN Young Investigators Awards research grant (Processo FAPESP) [2015/025271]
- CNPq [302927/2018-2]
Ask authors/readers for more resources
Chlorogenic acids (CGAs) and the biopolymer lignin are both products of the phenylpropanoid pathway. Whereas CGAs have been reported to play a role during stress responses, lignin is a major component of secondary cell walls, providing physical strength and hydrophobicity to supportive and water-conducting tissues. Because the chemical structure of CGAs largely resembles those of some lignin intermediates and because CGAs can be converted back to hydroxycinnamoyl-CoAs in vitro, CGAs have been considered authentic intermediates of the lignin biosynthetic pathway. However, it is still unclear whether and how the CGA pool can be channeled towards the production of lignin monomers in response to developmental or environmental signals. Comprehensive studies on the catalytic activity of recombinant enzymes together with functional characterizations in planta have been very useful in understanding the potential interdependence between these two metabolic routes. Here we present the current understanding on CGA metabolism and discuss the biochemical and molecular evidence of the metabolic re-routing of CGAs towards lignin.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available