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L Tang et al.
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MC Myzak et al.
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R Munday et al.
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Y Shinkai et al.
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Theresa A. Shapiro et al.
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V. V. Lyakhovich et al.
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SK Biswas et al.
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C Fimognari et al.
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AT Dinkova-Kostova et al.
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TW Kensler et al.
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HJ Kim et al.
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SD Cho et al.
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S Murata et al.
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A Ceriello et al.
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N Wakabayashi et al.
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MC Myzak et al.
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L Tao et al.
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MV Galan et al.
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SA Rushworth et al.
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RH Liu
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XL Chen et al.
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HC Hung et al.
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MK Kwak et al.
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G Bjelakovic et al.
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D Siegel et al.
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M Murashima et al.
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C Manach et al.
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H Sakurai et al.
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SA McNaughton et al.
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A Pastore et al.
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A Ceriello
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M Müller et al.
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Beneficial and adverse effects of chemopreventive agents
BM Lee et al.
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C Fimognari et al.
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JW Lampe et al.
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AT Dinkova-Kostova et al.
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JW Fahey et al.
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E Heiss et al.
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CW Nho et al.
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