cobalt-Catalyzed. Oxidative Annulation of Berizothiophene-[b]-1,1-dioxide through Diastereoselective Double C-H Activation

The use of inexpensive base metal catalysis to perform C H activation is an active field of research in organic synthesis. Described herein is a sustainable cobaltcatalyzed diastereoselective oxidative annulation/double C H activation of benzothiophene-[b]-1,1-dioxide with aminoquinolinamides under mild reaction conditions for the synthesis of annulated benzothiophenes.