4.8 Article

Light-Induced Intramolecular Iodine-Atom Transfer Radical Addition of Alkyne: An Approach from Aryl Iodide to Alkenyl Iodide

Journal

ORGANIC LETTERS
Volume 21, Issue 22, Pages 9133-9137

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b03519

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Funding

  1. Shanghai Science and Technology Committee [18DZ1201607]
  2. International Science & Technology Cooperation Program of China [2014DFE40130]

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A light-induced intramolecular iodine-atom transfer radical addition was reported toward iodine-substituted fluorene derivatives. A thioxanthone derivative was employed as a visible light sensitizer for this 5-exo-dig exclusive radical addition, and the newly formed vinyl iodide compounds were further proved to be effective partners for several cross-coupling reactions.

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