Journal
ORGANIC LETTERS
Volume 21, Issue 22, Pages 9124-9127Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b03511
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- University of Geneva
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A highly regioselective Ni-catalyzed hydro-alkoxylation of 1,3-dienes is reported. The use of a (P,N) ligand is essential in achieving high levels of selectivity. The optimized protocol operates under particularly mild conditions, it provides access to a broad range of structurally diverse allylic ethers, and tolerates a number of sensitive functional groups.
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