Related references
Note: Only part of the references are listed.Sarcopenia and Variation in the Human Leukocyte Antigen Complex
Garan Jones et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2020)
Polygenic predictors of age-related decline in cognitive ability
Stuart J. Ritchie et al.
MOLECULAR PSYCHIATRY (2020)
The effect of caloric restriction on working memory in healthy non-obese adults
Emilie Leclerc et al.
CNS SPECTRUMS (2020)
The Longevity-Associated SH2B3 (LNK) Genetic Variant: Selected Aging Phenotypes in 379,758 Subjects
Chia-Ling Kuo et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2020)
Novel Common Genetic Susceptibility Loci for Colorectal Cancer
Stephanie L. Schmit et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2019)
Use of an Alzheimer's disease polygenic risk score to identify mild cognitive impairment in adults in their 50s
Mark W. Logue et al.
MOLECULAR PSYCHIATRY (2019)
Novel Common Genetic Susceptibility Loci for Colorectal Cancer
Stephanie L. Schmit et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2019)
APOE Alleles and Extreme Human Longevity
Paola Sebastiani et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2019)
Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential
Frank Madeo et al.
CELL METABOLISM (2019)
A Quarter Century of APOE and Alzheimer's Disease: Progress to Date and the Path Forward
Michael E. Belloy et al.
NEURON (2019)
Benefits and limitations of genome-wide association studies
Vivian Tam et al.
NATURE REVIEWS GENETICS (2019)
Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan
Lei Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Genetic correlations of polygenic disease traits: from theory to practice
Wouter van Rheenen et al.
NATURE REVIEWS GENETICS (2019)
2 years of calorie restriction and cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial
William E. Kraus et al.
LANCET DIABETES & ENDOCRINOLOGY (2019)
A Prospective Analysis of Genetic Variants Associated with Human Lifespan
Kevin M. Wright et al.
G3-GENES GENOMES GENETICS (2019)
A meta-analysis of genome-wide association studies identifies multiple longevity genes
Joris Deelen et al.
NATURE COMMUNICATIONS (2019)
Leveraging Polygenic Functional Enrichment to Improve GWAS Power
Gleb Kichaev et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2019)
Hereditary Hemochromatosis Associations with Frailty, Sarcopenia and Chronic Pain: Evidence from 200,975 Older UK Biobank Participants
Jone Tamosauskaite et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2019)
Exceptional Human Longevity
Robert J. Pignolo
MAYO CLINIC PROCEEDINGS (2019)
Age-related remodelling of oesophageal epithelia by mutated cancer drivers
Akira Yokoyama et al.
NATURE (2019)
Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
Mengzhen Liu et al.
NATURE GENETICS (2019)
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Iris E. Jansen et al.
NATURE GENETICS (2019)
Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data
Ioanna Tachmazidou et al.
NATURE GENETICS (2019)
The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
Annalisa Buniello et al.
NUCLEIC ACIDS RESEARCH (2019)
Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait
Niels van den Berg et al.
NATURE COMMUNICATIONS (2019)
Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank
Luke C. Pilling et al.
BMJ-BRITISH MEDICAL JOURNAL (2019)
A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study
Zuyun Liu et al.
PLOS MEDICINE (2019)
Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances
Paul R. H. J. Timmers et al.
ELIFE (2019)
Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study
Jamie N. Justice et al.
EBIOMEDICINE (2019)
Obesity and Longer Term Risks of Dementia in 65-74 Year Olds
Kirsty Bowman et al.
AGE AND AGEING (2019)
Identification of 12 genetic loci associated with human healthspan
Aleksandr Zenin et al.
COMMUNICATIONS BIOLOGY (2019)
Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies
Harold Bae et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2018)
Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis
Daniel W. Belsky et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2018)
Genetic architecture: the shape of the genetic contribution to human traits and disease
Nicholas J. Timpson et al.
NATURE REVIEWS GENETICS (2018)
Healthy cognitive ageing in the Lothian Birth Cohort studies: marginal gains not magic bullet
J. Corley et al.
PSYCHOLOGICAL MEDICINE (2018)
Somatic Mutations and Clonal Hematopoiesis: Unexpected Potential New Drivers of Age-Related Cardiovascular Disease
Jose J. Fuster et al.
CIRCULATION RESEARCH (2018)
Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study
Anatoliy I. Yashin et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2018)
Back to the future: Epigenetic clock plasticity towards healthy aging
Ken Declerck et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2018)
Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity
Mary Revelas et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2018)
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Rainer Malik et al.
NATURE GENETICS (2018)
Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis
Eleni Zengini et al.
NATURE GENETICS (2018)
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
Fredrick R. Schumacher et al.
NATURE GENETICS (2018)
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
James J. Lee et al.
NATURE GENETICS (2018)
Quantitative analysis of population-scale family trees with millions of relatives
Joanna Kaplanis et al.
SCIENCE (2018)
TORC1 inhibition enhances immune function and reduces infections in the elderly
Joan B. Mannick et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Gail Davies et al.
NATURE COMMUNICATIONS (2018)
Somatic mutagenesis in satellite cells associates with human skeletal muscle aging
Irene Franco et al.
NATURE COMMUNICATIONS (2018)
Aging and the rise of somatic cancer-associated mutations in normal tissues
Rosa Ana Risques et al.
PLOS GENETICS (2018)
Genomic instability and DNA replication defects in progeroid syndromes
Romina Burla et al.
NUCLEUS (2018)
Mitochondrial Quality Control in Neurodegenerative Diseases: Focus on Parkinson's Disease and Huntington's Disease
Sandra Franco-Iborra et al.
FRONTIERS IN NEUROSCIENCE (2018)
Genomic instability and DNA replication defects in progeroid syndromes
Romina Burla et al.
NUCLEUS (2018)
Obesity and Cancer: Existing and New Hypotheses for a Causal Connection
Trevor W. Stone et al.
EBIOMEDICINE (2018)
Somatic Mutagenesis in Mammals and Its Implications for Human Disease and Aging
Lei Zhang et al.
ANNUAL REVIEW OF GENETICS, VOL 52 (2018)
Time and the Metrics of Aging
Luigi Ferrucci et al.
CIRCULATION RESEARCH (2018)
Genetics of Human Longevity Within an Eco-Evolutionary Nature-Nurture Framework
Cristina Giuliani et al.
CIRCULATION RESEARCH (2018)
Aging, Cell Senescence, and Chronic Disease Emerging Therapeutic Strategies
Tamara Tchkonia et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2018)
Understanding lamin proteins and their roles in aging and cardiovascular diseases
Yizhi Jiang et al.
LIFE SCIENCES (2018)
Genomic atlas of the human plasma proteome
Benjamin B. Sun et al.
NATURE (2018)
Facing up to the global challenges of ageing
Linda Partridge et al.
NATURE (2018)
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
Symen Ligthart et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2018)
Estimates of the Heritability of Human Longevity Are Substantially Inflated due to Assortative Mating
J. Graham Ruby et al.
GENETICS (2018)
The UK Biobank resource with deep phenotyping and genomic data
Clare Bycroft et al.
NATURE (2018)
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
Anubha Mahajan et al.
NATURE GENETICS (2018)
Somatic mutant clones colonize the human esophagus with age
Inigo Martincorena et al.
SCIENCE (2018)
LNK deficiency promotes acute aortic dissection and rupture
Fanny Laroumanie et al.
JCI INSIGHT (2018)
Obesity in Older People With and Without Conditions Associated With Weight Loss: Follow-up of 955,000 Primary Care Patients
Kirsty Bowman et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2017)
Four Genome-Wide Association Studies Identify New Extreme Longevity Variants
Paola Sebastiani et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2017)
The role of LNK/SH2B3 genetic alterations in myeloproliferative neoplasms and other hematological disorders
N. Maslah et al.
LEUKEMIA (2017)
Association analysis identifies 65 new breast cancer risk loci
Kyriaki Michailidou et al.
NATURE (2017)
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
Peter K. Joshi et al.
NATURE COMMUNICATIONS (2017)
Caloric restriction improves health and survival of rhesus monkeys
Julie A. Mattison et al.
NATURE COMMUNICATIONS (2017)
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
Sara M. Willems et al.
NATURE COMMUNICATIONS (2017)
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study
Philip C. Haycock et al.
JAMA ONCOLOGY (2017)
Werner syndrome: Clinical features, pathogenesis and potential therapeutic interventions
Junko Oshima et al.
AGEING RESEARCH REVIEWS (2017)
Human longevity: 25 genetic loci associated in 389,166 UK biobank participants
Luke C. Pilling et al.
AGING-US (2017)
Calorie restriction in humans: An update
Jasper Most et al.
AGEING RESEARCH REVIEWS (2017)
Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations
Susana Gonzalo et al.
AGEING RESEARCH REVIEWS (2017)
The complex genetics of gait speed: genome-wide meta-analysis approach
Dan Ben-Avraham et al.
AGING-US (2017)
Long live FOXO: unraveling the role of FOXO proteins in aging and longevity
Rute Martins et al.
AGING CELL (2016)
Age-related macular degeneration: genome-wide association studies to translation
James R. M. Black et al.
GENETICS IN MEDICINE (2016)
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
Lars G. Fritsche et al.
NATURE GENETICS (2016)
GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium
Amy M. Matteini et al.
AGING CELL (2016)
Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants
Luke C. Pilling et al.
AGING-US (2016)
Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2
Erik B. van den Akker et al.
BLOOD (2016)
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease
William J. Astle et al.
CELL (2016)
Dynamics of an Aging Genome
Amalio Telenti et al.
CELL METABOLISM (2016)
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Sarah J. Mitchell et al.
CELL METABOLISM (2016)
Current Understanding on Role of the Wnt Signaling Pathway Effector TCF7L2 in Glucose Homeostasis
Tianru Jin
ENDOCRINE REVIEWS (2016)
Longer-Lived Parents and Cardiovascular Outcomes
Janice L. Atkins et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)
Tissue-specific mutation accumulation in human adult stem cells during life
Francis Blokzijl et al.
NATURE (2016)
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
Darren J. Baker et al.
NATURE (2016)
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
Zhihong Zhu et al.
NATURE GENETICS (2016)
Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA
Morten Scheibye-Knudsen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Lessons from Genome-Wide Association Studies in Reproductive Medicine: Menopause
Katherine S. Ruth et al.
SEMINARS IN REPRODUCTIVE MEDICINE (2016)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
Cristian Pattaro et al.
NATURE COMMUNICATIONS (2016)
Prevalence and Costs of Skin Cancer Treatment in the US, 2002-2006 and 2007-2011
Gery P. Guy et al.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE (2015)
Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species
Harrison Pride et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Evolutionary aspects of ABO blood group in humans
Massimo Franchini et al.
CLINICA CHIMICA ACTA (2015)
Update on iron metabolism and molecular perspective of common genetic and acquired disorder, hemochromatosis
Seongseok Yun et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2015)
The long noncoding RNA regulation at the MYC locus
Jian-Feng Xiang et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2015)
Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology
Henriet Springelkamp et al.
GENETIC EPIDEMIOLOGY (2015)
Brain Health: The Importance of Recognizing Cognitive Impairment: An IAGG Consensus Conference
John E. Morley et al.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2015)
Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer
Rayjean J. Hung et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)
Genetic studies of body mass index yield new insights for obesity biology
Adam E. Locke et al.
NATURE (2015)
The support of human genetic evidence for approved drug indications
Matthew R. Nelson et al.
NATURE GENETICS (2015)
A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease
Majid Nikpay et al.
NATURE GENETICS (2015)
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
Felix R. Day et al.
NATURE GENETICS (2015)
An atlas of genetic correlations across human diseases and traits
Brendan Bulik-Sullivan et al.
NATURE GENETICS (2015)
The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease
James B. Stewart et al.
NATURE REVIEWS GENETICS (2015)
Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants
Ankita Bansal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The Concordance and Heritability of Type 2 Diabetes in 34,166 Twin Pairs From International Twin Registers: The Discordant Twin (DISCOTWIN) Consortium
Gonneke Willemsen et al.
TWIN RESEARCH AND HUMAN GENETICS (2015)
Probability and heritability estimates on primary osteoarthritis of the hip leading to total hip arthroplasty: a nationwide population based follow-up study in Danish twins
Soren Glud Skousgaard et al.
ARTHRITIS RESEARCH & THERAPY (2015)
Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity
Kristen Fortney et al.
PLOS GENETICS (2015)
Targeting senescent cells enhances adipogenesis and metabolic function in old age
Ming Xu et al.
ELIFE (2015)
Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer
Rayjean J. Hung et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)
Vascular cell adhesion molecule-1 (VCAM-1)-An increasing insight into its role in tumorigenicity and metastasis
Martin Schlesinger et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
'Obesity paradox' misunderstands the biology of optimal weight throughout the life cycle
J. B. Dixon et al.
INTERNATIONAL JOURNAL OF OBESITY (2015)
GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy
Linda Broer et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2015)
Aging children of long-lived parents experience slower cognitive decline
Ambarish Dutta et al.
ALZHEIMERS & DEMENTIA (2014)
Geroscience: Linking Aging to Chronic Disease
Brian K. Kennedy et al.
CELL (2014)
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age
Joris Deelen et al.
HUMAN MOLECULAR GENETICS (2014)
Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets
Nilufer Rahmioglu et al.
HUMAN REPRODUCTION UPDATE (2014)
Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing
Laura C. Greaves et al.
PLOS GENETICS (2014)
A novel diagnostic tool reveals mitochondrial pathology in human diseases and aging
Morten Scheibye-Knudsen et al.
AGING-US (2013)
Estimation and Partition of Heritability in Human Populations Using Whole-Genome Analysis Methods
Anna A. E. Vinkhuyzen et al.
ANNUAL REVIEW OF GENETICS, VOL 47 (2013)
Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect
Linda Broer et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2013)
ANRIL: Molecular Mechanisms and Implications in Human Health
Ada Congrains et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Modeling the Rate of Senescence: Can Estimated Biological Age Predict Mortality More Accurately Than Chronological Age?
Morgan E. Levine
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2013)
Longer Lived Parents: Protective Associations With Cancer Incidence and Overall Mortality
Ambarish Dutta et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2013)
Discovery and refinement of loci associated with lipid levels
Cristen J. Willer et al.
NATURE GENETICS (2013)
Identification of seven loci affecting mean telomere length and their association with disease
Veryan Codd et al.
NATURE GENETICS (2013)
The GH/IGF-1 axis in ageing and longevity
Riia K. Junnila et al.
NATURE REVIEWS ENDOCRINOLOGY (2013)
The heritability of human disease: estimation, uses and abuses
Albert Tenesa et al.
NATURE REVIEWS GENETICS (2013)
Variability of marine climate on the North Icelandic Shelf in a 1357-year proxy archive based on growth increments in the bivalve Arctica islandica
Paul G. Butler et al.
PALAEOGEOGRAPHY PALAEOCLIMATOLOGY PALAEOECOLOGY (2013)
Guidelines for Genome-Wide Association Studies
Gregory S. Barsh et al.
PLOS GENETICS (2012)
Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing
Lorna W. Harries et al.
AGING CELL (2011)
Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited
Joris Deelen et al.
AGING CELL (2011)
What is lifespan regulation and why does it exist?
Bruce A. Carnes
BIOGERONTOLOGY (2011)
Genome-wide association study identifies three new melanoma susceptibility loci
Jennifer H. Barrett et al.
NATURE GENETICS (2011)
Stability and Change in Intelligence From Age 11 to Ages 70, 79, and 87: The Lothian Birth Cohorts of 1921 and 1936
Alan J. Gow et al.
PSYCHOLOGY AND AGING (2011)
Fat tissue, aging, and cellular senescence
Tamara Tchkonia et al.
AGING CELL (2010)
Dissecting the role of mTOR: Lessons from mTOR inhibitors
Ryan J. O. Dowling et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)
LocusZoom: regional visualization of genome-wide association scan results
Randall J. Pruim et al.
BIOINFORMATICS (2010)
Extending Healthy Life Span-From Yeast to Humans
Luigi Fontana et al.
SCIENCE (2010)
Regulation of Lifespan, Metabolism, and Stress Responses by the Drosophila SH2B Protein, Lnk
Cathy Slack et al.
PLOS GENETICS (2010)
Objectively measured physical capability levels and mortality: systematic review and meta-analysis
Rachel Cooper et al.
BMJ-BRITISH MEDICAL JOURNAL (2010)
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C-elegans
Eric L. Greer et al.
AGING CELL (2009)
Circos: An information aesthetic for comparative genomics
Martin Krzywinski et al.
GENOME RESEARCH (2009)
Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15
Kaisu Keskitalo et al.
HUMAN MOLECULAR GENETICS (2009)
mTOR signaling at a glance
Mathieu Laplante et al.
JOURNAL OF CELL SCIENCE (2009)
The HLA genomic loci map: expression, interaction, diversity and disease
Takashi Shiina et al.
JOURNAL OF HUMAN GENETICS (2009)
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
David E. Harrison et al.
NATURE (2009)
Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis
Robert J. Pignolo et al.
AGING CELL (2008)
Aging and survival: The genetics of life span extension by dietary restriction
William Mair et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
African Genetic Diversity: Implications for Human Demographic History, Modern Human Origins, and Complex Disease Mapping
Michael C. Campbell et al.
Annual Review of Genomics and Human Genetics (2008)
Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers
Entela Bua et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2006)
Lamin A-dependent nuclear defects in human aging
P Scaffidi et al.
SCIENCE (2006)
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
Y Kraytsberg et al.
NATURE GENETICS (2006)
Role of genes and environments for explaining Alzheimer disease
M Gatz et al.
ARCHIVES OF GENERAL PSYCHIATRY (2006)
Evolutionary conservation of the clk-1-dependent mechanism of longevity:: loss of mclk1 increases cellular fitness and lifespan in mice
XX Liu et al.
GENES & DEVELOPMENT (2005)
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
J Campisi
CELL (2005)
eat-2 and eat-18 are required for nicotinic neurotransmission in the Caenorhabditis elegans pharynx
JP McKay et al.
GENETICS (2004)
Premature ageing in mice expressing defective mitochondrial DNA polymerase
A Trifunovic et al.
NATURE (2004)
Heritability of death from coronary heart disease: a 36-year follow-up of 20 966 Swedish twins
S Zdravkovic et al.
JOURNAL OF INTERNAL MEDICINE (2002)
Frailty in older adults: Evidence for a phenotype
LP Fried et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2001)
Lessons from human progeroid syndromes
GM Martin et al.
NATURE (2000)