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Oxidative Stress and Hypertension: Current Concepts
Ana M. Briones et al.
CURRENT HYPERTENSION REPORTS (2010)
Mitochondrial proton and electron leaks
Martin Jastroch et al.
ESSAYS IN BIOCHEMISTRY: MITOCHONDRIAL FUNCTION (2010)
Mitochondrial potassium channels and reactive oxygen species
Dominika Malinska et al.
FEBS LETTERS (2010)
NADPH oxidases in cardiovascular disease
Ralf P. Brandes et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Structure of the N-terminal Regulatory Domain of a Plant NADPH Oxidase and Its Functional Implications
Takashi Oda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
NADPH Oxidases Regulate CD44 and Hyaluronic Acid Expression in Thrombin-treated Vascular Smooth Muscle Cells and in Atherosclerosis
Aleksandr E. Vendrov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
Benoit Laleu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Netrin-1 prevents ischemia/reperfusion-induced myocardial infarction via a DCC/ERK1/2/eNOS(s1177)/NO/DCC feed-forward mechanism
Jun Zhang et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
Nox4-Derived H2O2 Mediates Endoplasmic Reticulum Signaling through Local Ras Activation
Ru-Feng Wu et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
S-glutathionylation uncouples eNOS and regulates its cellular and vascular function
Chun-An Chen et al.
NATURE (2010)
NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis
Min Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart
Junya Kuroda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy
M. Sedeek et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2010)
Sepiapterin reductase regulation of endothelial tetrahydrobiopterin and nitric oxide bioavailability
Ling Gao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Identification of Structural Elements in Nox1 and Nox4 Controlling Localization and Activity
Ina Helmcke et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells
Alicia N. Lyle et al.
CIRCULATION RESEARCH (2009)
Molecular mechanisms of hypertension: role of Nox family NADPH oxidases
Mona Sedeek et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2009)
Metallothionein Abrogates GTP Cyclohydrolase I Inhibition-Induced Cardiac Contractile and Morphological Defects Role of Mitochondrial Biogenesis
Asli F. Ceylan-Isik et al.
HYPERTENSION (2009)
Mitochondria-Targeted Antioxidant MitoQ10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy
Delyth Graham et al.
HYPERTENSION (2009)
Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
Ethan J. Anderson et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Mechanistic insights into folic acid-dependent vascular protection: Dihydrofolate reductase (DHFR)-mediated reduction in oxidant stress in endothelial cells and angiotensin II-infused mice: A novel HPLC-based fluorescent assay for DHFR activity
Ling Gao et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
NADPH oxidases and angiotensin II receptor signaling
Abel Martin Garrido et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2009)
Targeting reactive oxygen species in hypertension
Christian Delles et al.
ANTIOXIDANTS & REDOX SIGNALING (2008)
Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension
Eberhard Schulz et al.
ANTIOXIDANTS & REDOX SIGNALING (2008)
Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer
Sylvia Luxen et al.
CANCER RESEARCH (2008)
High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury
An L. Moens et al.
CIRCULATION (2008)
Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension
Yan-Hua Du et al.
CIRCULATION (2008)
Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction - Linking mitochondrial oxidative damage and vascular endothelial dysfunction
Abdulrahman K. Doughan et al.
CIRCULATION RESEARCH (2008)
Differential vascular functions of Nox family NADPH oxidases
Ralf P. Brandes et al.
CURRENT OPINION IN LIPIDOLOGY (2008)
Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cells
Desmond B. Jay et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production
Sergey I. Dikalov et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Involvement of Nox2 NADPH oxidase in adverse cardiac remodeling after myocardial infarction
Yee H. Looi et al.
HYPERTENSION (2008)
Acute inhibition of guanosine triphosphate cyclohydrolase 1 uncouples endothelial nitric oxide synthase and elevates blood pressure
Shuangxi Wang et al.
HYPERTENSION (2008)
Regulation of ROS signal transduction by NADPH oxidase 4 localization
Kai Chen et al.
JOURNAL OF CELL BIOLOGY (2008)
Impact of oxypurinol in patients with symptomatic heart failure
Joshua M. Hare et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)
Calcium-Dependent NOX5 Nicotinamide Adenine Dinucleotide Phosphate Oxidase Contributes to Vascular Oxidative Stress in Human Coronary Artery Disease
Tomasz J. Guzik et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)
Regulation of Nox and Duox enzymatic activity and expression
J. David Lambeth et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
NADPH oxidase inhibitors: New anti hypertensive agents?
Holly C. Williams et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2007)
A specific role for eNOS-derived reactive oxygen species in atherosclerosis progression
Tomofumi Takaya et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes
Alejandra San Martin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Endothelial Nox2 overexpression potentiates vascular oxidative stress and hemodynamic response to angiotensin II - Studies in endothelial-targeted Nox2 transgenic mice
Jennifer K. Bendall et al.
CIRCULATION RESEARCH (2007)
Oral administration of tetrahydrobiopterin slows the progression of atherosclerosis in apolipoprotein E-knockout mice
Yoshiyuki Hattori et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
NADPH oxidase 5 (NOX5) interacts with and is regulated by calmodulin
Fabiana Tirone et al.
FEBS LETTERS (2007)
Mitochondrial dysfunction in atherosclerosis
Nageswara R. Madamanchi et al.
CIRCULATION RESEARCH (2007)
Role of oxidative stress in the pathogenesis of abdominal aortic aneurysms
Michael L. McCormick et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
NOX5 variants are functionally active in endothelial cells
Rachida S. BelAiba et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Role of oxidative stress in cardiac hypertrophy and remodeling
Eiki Takimoto et al.
HYPERTENSION (2007)
Preconditioning protects endothelium by preventing ET-1-induced activation of NADPH oxidase and xanthine oxidase in post-ischemic heart
Monika Duda et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
Karen Bedard et al.
PHYSIOLOGICAL REVIEWS (2007)
Nox4 is required for maintenance of the differentiated vascular smooth muscle cell phenotype
Roza E. Clempus et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Attenuation of angiotensin II signaling recouples eNOS and inhibits nonendothelial NOX activity in diabetic mice
Jeong-Ho Oak et al.
DIABETES (2007)
被撤回的出版物: Uncoupling of endothelial nitric oxidase synthase by hypochlorous acid - Role of NAD(P)H oxidase-derived superoxide and peroxynitrite (Retracted article. See vol. 42, 2022)
Jian Xu et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies
David S. Shames et al.
PLOS MEDICINE (2006)
Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice
Betsy N. Perry et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2006)
MnSOD deficiency increases endothelial dysfunction in ApoE-deficient mice
Masuo Ohashi et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice
Mengwei Zang et al.
DIABETES (2006)
Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation
Henrik ten Freyhaus et al.
CARDIOVASCULAR RESEARCH (2006)
Identification of the maturation factor for dual oxidase - Evolution of an eukaryotic operon equivalent
Helmut Grasberger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Novel Nox inhibitor of oxLDL-induced reactive oxygen species formation in human endothelial cells
C Stielow et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Leptin, endothelin, NADPH oxidase, and heart failure
H Morawietz et al.
HYPERTENSION (2006)
Netrin-1 induces angiogenesis via a DCC-dependent ERK1/2-eNOS feed-forward mechanism
A Nguyen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Endothelin-I-induced oxidative stress in DOCA-salt hypertension involves NADPH-oxidase-independent mechanisms
GE Callera et al.
CLINICAL SCIENCE (2006)
Decreased blood pressure in NOX1-deficient mice
G Gavazzi et al.
FEBS LETTERS (2006)
Vascular NADPH oxidases as drug targets for novel antioxidant strategies
Tomasz J. Guzik et al.
DRUG DISCOVERY TODAY (2006)
Nox1 is involved in angiotensin II-mediated hypertension - A study in Nox1-deficient mice
K Matsuno et al.
CIRCULATION (2005)
Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice
A Dikalova et al.
CIRCULATION (2005)
Hydrogen peroxide regulation of endothelial function: Origins, mechanisms, and consequences
H Cai
CARDIOVASCULAR RESEARCH (2005)
A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation
YM Kim et al.
CIRCULATION RESEARCH (2005)
Monomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytes
PA Loughran et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Reactive oxygen species-linked regulation of the multidrug resistance transporter P-glycoprotein in Nox-1 overexpressing prostate tumor spheroids
M Wartenberg et al.
FEBS LETTERS (2005)
Endothelial dihydrofolate reductase: Critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase
K Chalupsky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The NADPH oxidase Nox3 constitutively produces superoxide in a p22Phox-dependent manner
N Ueno et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Pigment epithelium-derived factor (PEDF) blocks angiotensin II signaling in endothelial cells via suppression of NADPH oxidase: a novel anti-oxidative mechanism of PEDF
S Yamagishi et al.
CELL AND TISSUE RESEARCH (2005)
The pathobiology of diabetic complications - A unifying mechanism
M Brownlee
DIABETES (2005)
Long-term inhibition of RhoA attenuates vascular contractility by enhancing endothelial NO production in an intact rabbit mesenteric artery
N Shiga et al.
CIRCULATION RESEARCH (2005)
NAD(P)H oxidases in rat basilar arterial endothelial cells
T Ago et al.
STROKE (2005)
NAD(P)H oxidase-dependent self-propagation of hydrogen peroxide and vascular disease
H Cai
CIRCULATION RESEARCH (2005)
Expression and localization of NOX2 and NOX4 in primary human endothelial cells
JD Van Buul et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Mitochondria-derived reactive oxygen species and vascular MAP kinases - Comparison of angiotensin II and diazoxide
S Kimura et al.
HYPERTENSION (2005)
The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle
SHM Ellmark et al.
CARDIOVASCULAR RESEARCH (2005)
Angiotensin II-induced hypertrophy is potentiated in mice overexpressing p22(phox) in vascular smooth muscle
DS Weber et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)
Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22(phox) in mice
K Laude et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)
Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5)
B Bánfi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells
LL Hilenski et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Effects of tempol on renal angiotensinogen production in Dahl salt-sensitive rats
H Kobori et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice
NJ Alp et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Nox4 as the major catalytic component of an endothelial NAD(P)H oxidase
T Ago et al.
CIRCULATION (2004)
Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms
SS Barbieri et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy
LB Stull et al.
CIRCULATION RESEARCH (2004)
Allopurinol attenuates left ventricular remodeling and dysfunction after experimental myocardial infarction -: A new action for an old drug?
N Engberding et al.
CIRCULATION (2004)
Vascular ischaemia and reperfusion injury
HK Eltzschig et al.
BRITISH MEDICAL BULLETIN (2004)
Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
Y Gao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo - Effect on endothelial NAD(P)H oxidase system
M Higashi et al.
CIRCULATION RESEARCH (2003)
Translocation of glomerular p47phox and p67phox by protein kinase C-β activation is required for oxidative stress in diabetic nephropathy
M Kitada et al.
DIABETES (2003)
Gene transfer of human guanosine 5′-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension
JS Zheng et al.
CIRCULATION (2003)
The vascular NAD(P)H oxidases as therapeutic targets cardiovascular diseases
H Cai et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2003)
Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases
R Takeya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Increased myocardial NADPH oxidase activity in human heart failure
C Heymes et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2003)
c-Src induces phosphorylation and translocation of p47phox - Role in superoxide generation by angiotensin II in human vascular smooth muscle cells
RM Touyz et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2003)
Peroxynitrite and mitochondrial dysfunction in the pathogenesis of Parkinson's disease
M Ebadi et al.
ANTIOXIDANTS & REDOX SIGNALING (2003)
Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells
M Geiszt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Y Groemping et al.
CELL (2003)
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension
U Landmesser et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Increased Nox2 expression in human cardiomyocytes after acute myocardial infarction
PAJ Krijnen et al.
JOURNAL OF CLINICAL PATHOLOGY (2003)
Two novel proteins activate superoxide generation by the NADPH oxidase NOX1
B Bánfi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Activation of NADPH oxidase during progression of cardiac hypertrophy to failure
JM Li et al.
HYPERTENSION (2002)
Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are able to reduce superoxide anion production by NADPH oxidase in THP-1-derived monocytes
S Delbosc et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2002)
Angiotensin II stimulation of NAD(P)H oxidase activity - Upstream mediators
PN Seshiah et al.
CIRCULATION RESEARCH (2002)
Mitochondrial KATP channels:: role in cardioprotection
O Oldenburg et al.
CARDIOVASCULAR RESEARCH (2002)
Mitochondrial integrity and function in atherogenesis
SW Ballinger et al.
CIRCULATION (2002)
Phosphorylation of p47phox sites by PKC α, βII, δ, and ζ:: Effect on binding to p22phox and on NADPH oxidase activation
A Fontayne et al.
BIOCHEMISTRY (2002)
Oxidative stress in human abdominal aortic aneurysms - A potential mediator of aneurysmal remodeling
FJ Miller et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2002)
Cellular antioxidant effects of atorvastatin in vitro and in vivo
S Wassmann et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2002)
Characterization of the differentiated antioxidant profile of human saliva
RM Nagler et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Pivotal role of a gp91phox-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice
JK Bendall et al.
CIRCULATION (2002)
Coenzyme Q(10) improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus
GF Watts et al.
DIABETOLOGIA (2002)
Characteristics and superoxide-induced activation of reconstituted myocardial mitochondrial ATP-sensitive potassium channels
DX Zhang et al.
CIRCULATION RESEARCH (2001)
Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo
M Wingler et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat
RA Beswick et al.
HYPERTENSION (2001)
p47phox is required for atherosclerotic lesion progression in ApoE-/- mice
PA Barry-Lane et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
A Ca2+-activated NADPH oxidase in testis, spleen, and lymph nodes
B Bánfi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
S17834, a new inhibitor of cell adhesion and atherosclerosis that targets NADPH oxidase
AJ Cayatte et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2001)
Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O2- and systolic blood pressure in mice
FE Rey et al.
CIRCULATION RESEARCH (2001)
Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91 phox
WA Edens et al.
JOURNAL OF CELL BIOLOGY (2001)
Hypoxia-inducible factor 1-mediated inhibition of peroxisome proliferator-activated receptor α expression during hypoxia
S Narravula et al.
JOURNAL OF IMMUNOLOGY (2001)
Homologs of gp91phox:: cloning and tissue expression of Nox3, Nox4, and Nox5
GJ Cheng et al.
GENE (2001)
Marked elevation in cortical urate and xanthine oxidoreductase activity in experimental bacterial meningitis
S Christen et al.
BRAIN RESEARCH (2001)
Role of NADPH oxidase in the vascular hypertrophic and oxidative stress response to angiotensin II in mice
HD Wang et al.
CIRCULATION RESEARCH (2001)
Enhanced superoxide anion formation in vascular tissues from spontaneously hypertensive and desoxycorticosterone acetate-salt hypertensive rats
R Wu et al.
JOURNAL OF HYPERTENSION (2001)
Rac2 is an essential regulator of neutrophil nicotinamide adenine dinucleotide phosphate oxidase activation in response to specific signaling pathways
C Kim et al.
JOURNAL OF IMMUNOLOGY (2001)
Role of bound zinc in dimer stabilization but not enzyme activity of neuronal nitric-oxide synthase
B Hemmens et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Endothelial dysfunction in cardiovascular diseases - The role of oxidant stress
H Cai et al.
CIRCULATION RESEARCH (2000)
Reactive oxygen species (ROS)-induced ROS release: A new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes
DB Zorov et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
NADPH oxidase subunit, gp91phox homologue, preferentially expressed in human colon epithelial cells
H Kikuchi et al.
GENE (2000)
Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family
X De Deken et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall
A Görlach et al.
CIRCULATION RESEARCH (2000)
Identification of Renox, an NAD(P)H oxidase in kidney
M Geiszt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
T Nishikawa et al.
NATURE (2000)
Vascular NADH/NADPH oxidase is involved in enhanced superoxide production in spontaneously hypertensive rats
G Zalba et al.
HYPERTENSION (2000)
Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium
T Ide et al.
CIRCULATION RESEARCH (2000)
A mammalian H+ channel generated through alternative splicing of the NADPH oxidase homolog NOH-1
B Bánfi et al.
SCIENCE (2000)