4.5 Article

The influence of polymeric membrane gas spargers on hydrodynamics and mass transfer in bubble column bioreactors

Journal

BIOPROCESS AND BIOSYSTEMS ENGINEERING
Volume 39, Issue 4, Pages 613-626

Publisher

SPRINGER
DOI: 10.1007/s00449-016-1543-7

Keywords

Bubble column; Membrane sparger; Bubble size distribution; Interfacial area; Overall mass transfer coefficient

Funding

  1. Danish Council for Strategic Research

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Gas sparging performances of a flat sheet and tubular polymeric membranes were investigated in 3.1 m bubble column bioreactor operated in a semi batch mode. Air-water and air-CMC (Carboxymethyl cellulose) solutions of 0.5, 0.75 and 1.0 % w/w were used as interacting gas-liquid mediums. CMC solutions were employed in the study to simulate rheological properties of bioreactor broth. Gas holdup, bubble size distribution, interfacial area and gas-liquid mass transfer were studied in the homogeneous bubbly flow hydrodynamic regime with superficial gas velocity (U (G)) range of 0.0004-0.0025 m/s. The study indicated that the tubular membrane sparger produced the highest gas holdup and densely populated fine bubbles with narrow size distribution. An increase in liquid viscosity promoted a shift in bubble size distribution to large stable bubbles and smaller specific interfacial area. The tubular membrane sparger achieved greater interfacial area and an enhanced overall mass transfer coefficient (K (L)a) by a factor of 1.2-1.9 compared to the flat sheet membrane.

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