Related references
Note: Only part of the references are listed.The Combination of MEK Inhibitor With Immunomodulatory Antibodies Targeting Programmed Death 1 and Programmed Death Ligand 1 Results in Prolonged Survival in Kras/p53-Driven Lung Cancer
Jong Woo Lee et al.
JOURNAL OF THORACIC ONCOLOGY (2019)
Cancer-cell-secreted CXCL11 promoted CD8+ T cells infiltration through docetaxel-induced-release of HMGB1 in NSCLC
Qun Gao et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Intratumor heterogeneity and tissue distribution of KRAS mutation in non-small cell lung cancer: implications for detection of mutated KRAS oncogene in exhaled breath condensate
Jacek Kordiak et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2019)
Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor
Matthew R. Janes et al.
CELL (2018)
The reactivity-driven biochemical mechanism of covalent KRAS(G12C) inhibitors
Rasmus Hansen et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
The reactivity-driven biochemical mechanism of covalent KRAS(G12C) inhibitors
Rasmus Hansen et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1-and RAS-driven cancers
Robert J. Nichols et al.
NATURE CELL BIOLOGY (2018)
Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions
Paul A. Jackson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery
Suzanne I. S. Mosely et al.
CANCER IMMUNOLOGY RESEARCH (2017)
AACR Project GENIE: Powering Precision Medicine through an International Consortium
Fabrice Andre et al.
CANCER DISCOVERY (2017)
Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States
Daniel R. Gentile et al.
CELL CHEMICAL BIOLOGY (2017)
RAS Proteins and Their Regulators in Human Disease
Dhirendra K. Simanshu et al.
CELL (2017)
Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy
Stefani Spranger et al.
CANCER CELL (2017)
MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade
Peter J. R. Ebert et al.
IMMUNITY (2016)
Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology
Mark J. Selby et al.
PLOS ONE (2016)
Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State
Matthew P. Patricelli et al.
CANCER DISCOVERY (2016)
The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4
Li Liu et al.
CLINICAL CANCER RESEARCH (2015)
Systematic Study of the Glutathione (GSH) Reactivity of N-Arylacrylamides: 1. Effects of Aryl Substitution
Victor J. Cee et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib
Caroline Robert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Management of BRAF and MEK inhibitor toxicities in patients with metastatic melanoma
Sarah J. Welsh et al.
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2015)
Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance
Phillip A. Schwartz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways
Anne Y. Saiki et al.
ONCOTARGET (2014)
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
Jonathan M. Ostrem et al.
NATURE (2013)
Metastatic colorectal cancer KRAS genotyping in routine practice: results and pitfalls
Aude Lamy et al.
MODERN PATHOLOGY (2011)
Intra-tumoral heterogeneity of KRAS and BRAF mutation status in patients with advanced colorectal cancer (aCRC) and cost-effectiveness of multiple sample testing
Susan D. Richman et al.
ANALYTICAL CELLULAR PATHOLOGY (2011)
KRAS Mutations and Susceptibility to Cetuximab and Panitumumab in Colorectal Cancer
Antonio Jimeno et al.
CANCER JOURNAL (2009)
SnapShot: Ras signaling
Megan Cully et al.
CELL (2008)
Signal transduction - The guanine nucleotide-binding switch in three dimensions
IR Vetter et al.
SCIENCE (2001)