4.4 Article

Isolation and structure elucidation of a new flavonol glycoside from Sabia Parviflora

Journal

NATURAL PRODUCT RESEARCH
Volume 35, Issue 14, Pages 2408-2413

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2019.1679130

Keywords

Sabia parviflora; flavonol glycoside; antioxidant; DPPH; ABTS plus

Funding

  1. National Natural Science Foundation of China [81560707]
  2. research center of preservation of germplasm resources and Evaluation in Traditional Chinese Medicine and Ethnomedicine, Guizhou Province [KY (2017) 018]
  3. project of Top-ranking Construction Discipline of Guizhou Province [GNYL (2017) 008]

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A new flavonol glycoside, Sabiapside A, and four known compounds were isolated from Sabia parviflora, showing higher antioxidant activities compared to vitamin C. This finding is significant for studying the pharmacology and health benefits of natural products from plants.
A new flavonol glycoside named Sabiapside A (1), along with four known compounds, quercetin-3-O-gentiobioside (2), camellianoside (3), isobariclisin-3-O- rutinoside (4), tsubakioside A (5), was isolated from Sabia parviflora. Their structures were elucidated by extensive spectroscopic analysis including MS, UV, IR and NMR data. The antioxidant activities of these glycosides evaluated by ABTS(+) and DPPH radical scavenging reaction was higher than that of vitamin C used as the reference antioxidant.

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