Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 20, Issue 7, Pages 532-565Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389557519666191122125453
Keywords
Benzimidazole; biological activity; anti-tuberculosis activity; anti-HIV activity; anti-malarial activity; antidiabetic
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Funding
- Rajiv Gandhi National Fellowship [RGNF-2014-15-ST-GUJ-57277]
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In the last 2-3 decades, the broad research in the application of benzimidazole derivatives made it important for mankind. Many scientists have worked on benzimidazole derivatives and they found that this compound has a diverse role in the field of medicinal chemistry. Few benzimidazole derivatives are currently in the market as a drug candidate against various diseases. Moreover, the benzimidazole derivatives exhibit pharmacological activities such as anti-tuberculosis, anti-malarial, antihistamine, antimicrobial, antiviral, antidiabetic, anticancer, anti-fungal, anti-inflammatory, analgesic, anti-HIV, etc. In this review, we have summarized various derivatives of benzimidazole which have been prepared by many researchers to understand the chemistry as well as diverse pharmacological activities. These findings may lead the scientists who are working in the field of medicinal chemistry to the development of benzimidazole based drug candidates in the future.
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