4.6 Review

Pharmacologically Aware Phage Therapy: Pharmacodynamic and Pharmacokinetic Obstacles to Phage Antibacterial Action in Animal and Human Bodies

Related references

Note: Only part of the references are listed.
Review Pharmacology & Pharmacy

Use of phage therapy to treat long-standing, persistent, or chronic bacterial infections

Stephen T. Abedon

ADVANCED DRUG DELIVERY REVIEWS (2019)

Article Biotechnology & Applied Microbiology

Isolation, characterization and efficacy of phage MJ2 against biofilm forming multi-drug resistant Enterobacter cloacae

Muhsin Jamal et al.

FOLIA MICROBIOLOGICA (2019)

Review Microbiology

Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria

Kaitlyn E. Kortright et al.

CELL HOST & MICROBE (2019)

Article Pharmacology & Pharmacy

Antimicrobial assessment of phage therapy using a porcine model of biofilm infection

C. Milho et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

Article Biochemistry & Molecular Biology

Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus

Rebekah M. Dedrick et al.

NATURE MEDICINE (2019)

Review Virology

Current State of Compassionate Phage Therapy

Shawna McCallin et al.

VIRUSES-BASEL (2019)

Article Dermatology

Bacteriophage Therapy of Chronic Nonhealing Wound: Clinical Study

Pooja Gupta et al.

INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS (2019)

Article Biotechnology & Applied Microbiology

Bacteriophages engineered to display foreign peptides may become short-circulating phages

Katarzyna Hodyra-Stefaniak et al.

MICROBIAL BIOTECHNOLOGY (2019)

Article Gastroenterology & Hepatology

Role of the microbiome in human development

Maria Gloria Dominguez-Bello et al.

Review Virology

Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System

Jonas D. Van Belleghem et al.

VIRUSES-BASEL (2019)

Review Biotechnology & Applied Microbiology

Bacteriophage-host arm race: an update on the mechanism of phage resistance in bacteria and revenge of the phage with the perspective for phage therapy

Aa Haeruman Azam et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2019)

Review Microbiology

Anti-CRISPR: discovery, mechanism and function

April Pawluk et al.

NATURE REVIEWS MICROBIOLOGY (2018)

Editorial Material Virology

Phage Therapy Faces Evolutionary Challenges

Clara Torres-Barcelo

VIRUSES-BASEL (2018)

Article Multidisciplinary Sciences

Extensive impact of non-antibiotic drugs on human gut bacteria

Lisa Maier et al.

NATURE (2018)

Article Microbiology

Adapted Bacteriophages for Treating Urinary Tract Infections

Aleksandre Ujmajuridze et al.

FRONTIERS IN MICROBIOLOGY (2018)

Article Medicine, General & Internal

Our missing microbes: Short-term antibiotic courses have long-term consequences

Martin J. Blaser

CLEVELAND CLINIC JOURNAL OF MEDICINE (2018)

Editorial Material Multidisciplinary Sciences

Preserving microbial diversity

Maria G. Dominguez Bello et al.

SCIENCE (2018)

Review Immunology

Bacteriophage Therapy: Clinical Trials and Regulatory Hurdles

Lucy L. Furfaro et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2018)

Article Evolutionary Biology

Phage treatment of an aortic graft infected with & IT;Pseudomonas aeruginosa & IT;

Benjamin K. Chan et al.

EVOLUTION MEDICINE AND PUBLIC HEALTH (2018)

Article Infectious Diseases

Silk Route to the Acceptance and Re-Implementation of Bacteriophage Therapy-Part II

Wilbert Sybesma et al.

ANTIBIOTICS-BASEL (2018)

Review Pharmacology & Pharmacy

Inhaled phage therapy: a promising and challenging approach to treat bacterial respiratory infections

Elsa Bodier-Montagutelli et al.

EXPERT OPINION ON DRUG DELIVERY (2017)

Article Microbiology

Antiphage activity of sera during phage therapy in relation to its outcome

Marzanna Lusiak-Szelachowska et al.

FUTURE MICROBIOLOGY (2017)

Review Biotechnology & Applied Microbiology

The antibiotic resistance crisis, with a focus on the United States

Evan Martens et al.

JOURNAL OF ANTIBIOTICS (2017)

Article Biology

Modeling the synergistic elimination of bacteria by phage and the innate immune system

Chung Yin (Joey) Leung et al.

JOURNAL OF THEORETICAL BIOLOGY (2017)

Article Multidisciplinary Sciences

Permeation of macromolecules into the renal glomerular basement membrane and capture by the tubules

Marlon G. Lawrence et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Review Oncology

Combination therapy in combating cancer

Reza Bayat Mokhtari et al.

ONCOTARGET (2017)

Article Multidisciplinary Sciences

Microencapsulation with alginate/CaCO3: A strategy for improved phage therapy

Joan Colom et al.

SCIENTIFIC REPORTS (2017)

Article Microbiology

Bacteriophage Clinical Use as Antibacterial Drugs: Utility and Precedent

Stephen T. Abedon

MICROBIOLOGY SPECTRUM (2017)

Article Chemistry, Medicinal

Information Phage Therapy Research Should Report

Stephen T. Abedon

PHARMACEUTICALS (2017)

Article Chemistry, Physical

Formulation, stabilisation and encapsulation of bacteriophage for phage therapy

Danish J. Malik et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2017)

Review Pharmacology & Pharmacy

Advances in the transepithelial transport of nanoparticles

Miaorong Yu et al.

DRUG DISCOVERY TODAY (2016)

Editorial Material Microbiology

Extending the lifetime of antibiotics: how can phage therapy help?

Benjamin K. Chan et al.

FUTURE MICROBIOLOGY (2016)

Article Respiratory System

Inhalation Study of Mycobacteriophage D29 Aerosol for Mice by Endotracheal Route and Nose-Only Exposure

Ke-yang Liu et al.

JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY (2016)

Review Infectious Diseases

Alternatives to antibiotics-a pipeline portfolio review

Lloyd Czaplewski et al.

LANCET INFECTIOUS DISEASES (2016)

Review Microbiology

Genetically Engineered Phages: a Review of Advances over the Last Decade

Diana P. Pires et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2016)

Article Microbiology

Therapeutic effect of Pseudomonas aeruginosa phage YH30 on mink hemorrhagic pneumonia

Jingmin Gu et al.

VETERINARY MICROBIOLOGY (2016)

Review Genetics & Heredity

The healthy human microbiome

Jason Lloyd-Price et al.

GENOME MEDICINE (2016)

Review Microbiology

Correlations of Host Genetics and Gut Microbiome Composition

Krystyna Dabrowska et al.

FRONTIERS IN MICROBIOLOGY (2016)

Article Microbiology

T4 Phage Tail Adhesin Gp12 Counteracts LPS-Induced Inflammation In Vivo

Paulina Miernikiewicz et al.

FRONTIERS IN MICROBIOLOGY (2016)

Article Microbiology

More Is Better: Selecting for Broad Host Range Bacteriophages

Alexa Ross et al.

FRONTIERS IN MICROBIOLOGY (2016)

Article Dermatology

Bacteriophage treatment of intransigent diabetic toe ulcers: a case series

R. Fish et al.

Journal of Wound Care (2016)

Article Multidisciplinary Sciences

Experimental Phage Therapy for Burkholderia pseudomallei Infection

Ong Guang-Han et al.

PLOS ONE (2016)

Review Critical Care Medicine

Antibiotic strategies in the era of multidrug resistance

George Karam et al.

CRITICAL CARE (2016)

Review Microbiology

Safety and efficacy of phage therapy via the intravenous route

Peter Speck et al.

FEMS MICROBIOLOGY LETTERS (2016)

Article Biotechnology & Applied Microbiology

Liposome-Encapsulated Bacteriophages for Enhanced Oral Phage Therapy against Salmonella spp.

Joan Colom et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2015)

Article Biotechnology & Applied Microbiology

A non-chromatographic method for the removal of endotoxins from bacteriophages

Steven D. Branston et al.

BIOTECHNOLOGY AND BIOENGINEERING (2015)

Review Microbiology

Antibiotics, Pediatric Dysbiosis, and Disease

Pajau Vangay et al.

CELL HOST & MICROBE (2015)

Article Microbiology

Phages targeting infected tissues: novel approach to phage therapy

Andrzej Gorski et al.

FUTURE MICROBIOLOGY (2015)

Editorial Material Microbiology

Re-establishing a place for phage therapy in western medicine

Elizabeth Martin Kutter et al.

FUTURE MICROBIOLOGY (2015)

Article Virology

Dark Matter of the Biosphere: the Amazing World of Bacteriophage Diversity

Graham F. Hatfull

JOURNAL OF VIROLOGY (2015)

Editorial Material Immunology

The lymph node filter revealed

Miroslav Hons et al.

NATURE IMMUNOLOGY (2015)

Article Chemistry, Multidisciplinary

Quality and Safety Requirements for Sustainable Phage Therapy Products

Jean-Paul Pirnay et al.

PHARMACEUTICAL RESEARCH (2015)

Article Multidisciplinary Sciences

Mammalian Host-Versus-Phage immune response determines phage fate in vivo

Katarzyna Hodyra-Stefaniak et al.

SCIENTIFIC REPORTS (2015)

Article Multidisciplinary Sciences

Removal of Endotoxins from Bacteriophage Preparations by Extraction with Organic Solvents

Bozena Szermer-Olearnik et al.

PLOS ONE (2015)

Article Ophthalmology

Corneal Infection Therapy with Topical Bacteriophage Administration

Ali Fadlallah et al.

OPEN OPHTHALMOLOGY JOURNAL (2015)

Article Microbiology

Aerosol Phage Therapy Efficacy in Burkholderia cepacia Complex Respiratory Infections

Diana D. Semler et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)

Article Microbiology

Comparative analysis of different oral approaches to treat Vibrio cholerae infection in adult mice

Abhishek Jaiswal et al.

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2014)

Review Infectious Diseases

Viruses versus bacteria-novel approaches to phage therapy as a tool against multidrug-resistant pathogens

Tania Mareike Viertel et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2014)

Article Virology

Immunogenicity Studies of Proteins Forming the T4 Phage Head Surface

Krystyna Dabrowska et al.

JOURNAL OF VIROLOGY (2014)

Article Biotechnology & Applied Microbiology

Taking Bacteriophage Therapy Seriously: A Moral Argument

Gilbert Verbeken et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Article Virology

Remarkable Mechanisms in Microbes to Resist Phage Infections

Ron L. Dy et al.

ANNUAL REVIEW OF VIROLOGY, VOL 1 (2014)

Review Biology

Phage Therapy: Eco-Physiological Pharmacology

Stephen T. Abedon

SCIENTIFICA (2014)

Article Microbiology

Predicting In Vivo Efficacy of Therapeutic Bacteriophages Used To Treat Pulmonary Infections

Marine Henry et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)

Review Microbiology

Phage cocktails and the future of phage therapy

Benjamin K. Chan et al.

FUTURE MICROBIOLOGY (2013)

Review Microbiology

Revenge of the phages: defeating bacterial defences

Julie E. Samson et al.

NATURE REVIEWS MICROBIOLOGY (2013)

Article Multidisciplinary Sciences

Oral delivery system prolongs blood circulation of docetaxel nanocapsules via lymphatic absorption

Suha Attili-Qadri et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Microbiology

A Quorum-Sensing-Induced Bacteriophage Defense Mechanism

Nina Molin Hoyland-Kroghsbo et al.

Article Immunology

Importance of prophages to evolution and virulence of bacterial pathogens

Louis-Charles Fortier et al.

VIRULENCE (2013)

Article Infectious Diseases

Phage Therapy Is Effective against Infection by Mycobacterium ulcerans in a Murine Footpad Model

Gabriela Trigo et al.

PLOS NEGLECTED TROPICAL DISEASES (2013)

Review Oncology

Tumor-penetrating peptides

Tambet Teesalu et al.

FRONTIERS IN ONCOLOGY (2013)

Review Chemistry, Multidisciplinary

Peptides as Targeting Elements and Tissue Penetration Devices for Nanoparticles

Erkki Ruoslahti

ADVANCED MATERIALS (2012)

Article Biochemistry & Molecular Biology

Identification of peptide sequences that target to the brain using in vivo phage display

Jingwei Li et al.

AMINO ACIDS (2012)

Article Biotechnology & Applied Microbiology

A test for the physiological phagemia hypothesis-natural intestinal coliphages do not penetrate to the blood in horses

M. Letarova et al.

FOLIA MICROBIOLOGICA (2012)

Article Multidisciplinary Sciences

Structure, function and diversity of the healthy human microbiome

Curtis Huttenhower et al.

NATURE (2012)

Review Microbiology

Going viral: next-generation sequencing applied to phage populations in the human gut

Alejandro Reyes et al.

NATURE REVIEWS MICROBIOLOGY (2012)

Article Engineering, Biomedical

Targeting the brain with PEG-PLGA nanoparticles modified with phage-displayed peptides

Jingwei Li et al.

BIOMATERIALS (2011)

Article Biotechnology & Applied Microbiology

The influence of external factors on bacteriophages-review

E. Jonczyk et al.

FOLIA MICROBIOLOGICA (2011)

Review Microbiology

Role of bacteriophage-encoded exotoxins in the evolution of bacterial pathogens

Veronica Casas et al.

FUTURE MICROBIOLOGY (2011)

Article Microbiology

Bacteriophage therapy for refractory Pseudomonas aeruginosa urinary tract infection

A. Khawaldeh et al.

JOURNAL OF MEDICAL MICROBIOLOGY (2011)

Article Microbiology

Antibacterial efficacy of lytic Pseudomonas bacteriophage in normal and neutropenic mice models

Birendra R. Tiwari et al.

JOURNAL OF MICROBIOLOGY (2011)

Editorial Material Chemistry, Multidisciplinary

The Phage Therapy Paradigm: Prt-A -Porter or Sur-mesure?

Jean-Paul Pirnay et al.

PHARMACEUTICAL RESEARCH (2011)

Review Pharmacology & Pharmacy

Phage therapy: delivering on the promise

D. R. Harper et al.

THERAPEUTIC DELIVERY (2011)

Review Microbiology

Bacteriophages and cancer

Paulina Budynek et al.

ARCHIVES OF MICROBIOLOGY (2010)

Review Biochemistry & Molecular Biology

Designing Phage Therapeutics

Lawrence D. Goodridge

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2010)

Review Biochemistry & Molecular Biology

Phage Therapy Pharmacology

Stephen T. Abedon et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2010)

Review Biochemistry & Molecular Biology

Bacteriophage for Biocontrol of Foodborne Pathogens: Calculations and Considerations

Steven Hagens et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2010)

Review Biochemistry & Molecular Biology

Phage Choice, Isolation, and Preparation for Phage Therapy

Jason J. Gill et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2010)

Review Biochemistry & Molecular Biology

Phage Therapy in Clinical Practice: Treatment of Human Infections

Elizabeth Kutter et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2010)

Article Biotechnology & Applied Microbiology

Oral Delivery Systems for Encapsulated Bacteriophages Targeted at Escherichia coli O157:H7 in Feedlot Cattle

K. Stanford et al.

JOURNAL OF FOOD PROTECTION (2010)

Article Immunology

Bacteriophage Therapy of Salmonella enterica: A Fresh Appraisal of Bacteriophage Therapy

Rosanna Capparelli et al.

JOURNAL OF INFECTIOUS DISEASES (2010)

Article Immunology

Bacteriophages Can Treat and Prevent Pseudomonas aeruginosa Lung Infections

Laurent Debarbieux et al.

JOURNAL OF INFECTIOUS DISEASES (2010)

Article Immunology

Efficacy of Bacteriophage Therapy in a Model of Burkholderia cenocepacia Pulmonary Infection

Lisa A. Carmody et al.

JOURNAL OF INFECTIOUS DISEASES (2010)

Review Microbiology

Bacteriophage resistance mechanisms

Simon J. Labrie et al.

NATURE REVIEWS MICROBIOLOGY (2010)

Article Agriculture, Dairy & Animal Science

Immune interference of bacteriophage efficacy when treating colibacillosis in poultry

W. E. Huff et al.

POULTRY SCIENCE (2010)

Article Multidisciplinary Sciences

Paradoxical glomerular filtration of carbon nanotubes

Alessandro Ruggiero et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Pharmacology & Pharmacy

Phage therapy

John N. Housby et al.

DRUG DISCOVERY TODAY (2009)

Review Clinical Neurology

Convection-enhanced delivery for the treatment of brain tumors

Waldemar Debinski et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2009)

Article Agriculture, Dairy & Animal Science

The influence of the mode of administration in the dissemination of three coliphages in chickens

A. Oliveira et al.

POULTRY SCIENCE (2009)

Review Multidisciplinary Sciences

Antibiotics for Emerging Pathogens

Michael A. Fischbach et al.

SCIENCE (2009)

Article Veterinary Sciences

Bacteriophage Treatment Reduces Salmonella Colonization of Infected Chickens

C. Borie et al.

AVIAN DISEASES (2008)

Article Biotechnology & Applied Microbiology

PEGylation of bacteriophages increases blood circulation time and reduces T-helper type 1 immune response

Kwang-Pyo Kim et al.

MICROBIAL BIOTECHNOLOGY (2008)

Review Biotechnology & Applied Microbiology

Combination drugs, an emerging option for antibacterial therapy

Guillaume Cottarel et al.

TRENDS IN BIOTECHNOLOGY (2007)

Article Biotechnology & Applied Microbiology

Renal clearance of quantum dots

Hak Soo Choi et al.

NATURE BIOTECHNOLOGY (2007)

Article Microbiology

Experimental phage therapy against Staphylococcus aureus in mice

Rosanna Capparelli et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)

Article Biotechnology & Applied Microbiology

Bacteriophage therapy to reduce Salmonella colonization of broiler chickens

R. J. Atterbury et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2007)

Article Microbiology

Phage therapy of Pseudomonas aeruginosa infection in a mouse burn wound model

Catherine S. McVay et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)

Article Microbiology

Hoc protein regulates the biological effects of T4 phage in mammals

Krystyna Dabrowska et al.

ARCHIVES OF MICROBIOLOGY (2007)

Article Biology

Pharmacodynarnics of non-replicating viruses, bacteriocins and lysins

James J. Bull et al.

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2006)

Article Virology

Possible association between phages, Hoc protein, and the immune system

K Dabrowska et al.

ARCHIVES OF VIROLOGY (2006)

Article Biotechnology & Applied Microbiology

Escherichia coli K1's capsule is a barrier to bacteriophage T7

D Scholl et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2005)

Article Microbiology

Human volunteers receiving Escherichia coli phage T4 orally:: a safety test of phage therapy

A Bruttin et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)

Review Biochemical Research Methods

Marine phage genomics: what have we learned?

JH Paul et al.

CURRENT OPINION IN BIOTECHNOLOGY (2005)

Article Immunology

The role of the complement system in innate immunity

H Rus et al.

IMMUNOLOGIC RESEARCH (2005)

Article Biochemical Research Methods

Identification of peptide sequences that induce the transport of phage across the gastrointestinal mucosal barrier

DM Duerr et al.

JOURNAL OF VIROLOGICAL METHODS (2004)

Review Microbiology

Population and evolutionary dynamics of phage therapy

BR Levin et al.

NATURE REVIEWS MICROBIOLOGY (2004)

Article Biotechnology & Applied Microbiology

Stability and activity of an Enterobacter aerogenes-specific bacteriophage under simulated gastro-intestinal conditions

K Verthé et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2004)

Article Microbiology

In vitro and in vivo bacteriolytic activities of Escherichia coli phages:: Implications for phage therapy

S Chibani-Chennoufi et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)

Review Microbiology

Ecology of prokaryotic viruses

MG Weinbauer

FEMS MICROBIOLOGY REVIEWS (2004)

Article Biotechnology & Applied Microbiology

Bacteriophage ecology in commercial sauerkraut fermentations

Z Lu et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2003)

Article Microbiology

In vivo antibacterial activity of with activity against RWJ-54428, a new cephalosporin gram-positive bacteria

DC Griffith et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)

Review Biochemistry & Molecular Biology

Marine phage genomics

JH Paul et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY (2002)

Article Agriculture, Dairy & Animal Science

Prevention of Escherichia coli infection in broiler chickens with a bacteriophage aerosol spray

WE Huff et al.

POULTRY SCIENCE (2002)

Article Multidisciplinary Sciences

Filamentous phage as vector-mediated antibody delivery to the brain

D Frenkel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Immunology

The antibody response to bacteriophage is linked to the lymphopenia gene in congenic BioBreeding rats

L Clark et al.

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY (2002)

Article Multidisciplinary Sciences

Targeting the prostate for destruction through a vascular address

W Arap et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemistry & Molecular Biology

Steps toward mapping the human vasculature by phage display

W Arap et al.

NATURE MEDICINE (2002)

Article Biology

Understanding bacteriophage therapy as a density-dependent kinetic process

RJH Payne et al.

JOURNAL OF THEORETICAL BIOLOGY (2001)

Article Biotechnology & Applied Microbiology

The interactions of peptides with the innate immune system studied with use of T7 phage peptide display

AV Sokoloff et al.

MOLECULAR THERAPY (2000)

Article Biotechnology & Applied Microbiology

Isolation of bacteriophages specific to a fish pathogen, Pseudomonas plecoglossicida, as a candidate for disease control

SC Park et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2000)

Article Pharmacology & Pharmacy

Phage therapy: The peculiar kinetics of self-replicating pharmaceuticals

RJH Payne et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2000)