Journal
MEDICINAL RESEARCH REVIEWS
Volume 40, Issue 3, Pages 909-930Publisher
WILEY
DOI: 10.1002/med.21642
Keywords
cancer; molecular imaging; multimodality imaging; nanoparticles; targeted therapy
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Funding
- National Natural Science Foundation of China [81630049]
- China Scholarship Council [201506160013]
- Ming Hsieh Institute Grant for Research of Engineering Medicine for Cancer
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This review explores recent work directed toward the development of nanoparticles (NPs) for multimodality cancer imaging and targeted cancer therapy. In the growing era of precision medicine, theranostics, or the combined use of targeted molecular probes in diagnosing and treating diseases is playing a particularly powerful role. There is a growing interest, particularly over the past few decades, in the use of NPs as theranostic tools due to their excellent performance in receptor target specificity and reduction in off-target effects when used as therapeutic agents. This review discusses recent advances, as well as the advantages and challenges of the application of NPs in cancer imaging and therapy.
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