Journal
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
Volume 109, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.msec.2019.110423
Keywords
Orthopedic screws; Poly(l-lactic acid); Syndesmosis; Biodegradable; Ligament injury
Categories
Funding
- Indo-US Science and Technology Forum [JC-26-2014]
- National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health [R01EB020640]
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Anterior cruciate ligament (ACL) plays a crucial role stabilizing the knee joint while connecting tibia to femur. Lack of proper treatment of injured ACL can lead to meniscus tear and osteoarthritis. Interference screws secure the graft tissue for superior integration of graft on host tissue during autograft fixation. Metal interference screws come with various disadvantages like mechanical load mismatch, graft laceration, secondary surgical removal and hindrance during MRI and CT post-operative scan. Though biodegradable polymeric screws provide various advantages their clinical outcomes reveal unprecedented complications for long term use of such screws. This review highlights polymer and composite screw currently available for surgical fixations and associated adverse reactions with the proposed mechanism for tunnel enlargement, effusion, osteolysis in ligament repairs. The need for suitable material engineering for development of orthopedic screws for successful rigid fixation has been highlighted in this review.
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