Journal
MARINE DRUGS
Volume 17, Issue 11, Pages -Publisher
MDPI
DOI: 10.3390/md17110636
Keywords
marine-derived fungi; marine natural products; anti-inflammatory
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Funding
- Natural Science Foundation of China [41776168, 41706167]
- National College Students' Innovation and Entrepreneurship Training Program
- Program of Xinmiao Talents in Zhejiang Province
- Ningbo Public Service Platform for High-Value Utilization of Marine Biological Resources [NBHY-2017-P2]
- National 111 Project of China [D16013]
- Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Development Fund
- K.C. Wong Magna Fund in Ningbo University
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Inflammation is a generalized, nonspecific, and beneficial host response of foreign challenge or tissue injury. However, prolonged inflammation is undesirable. It will cause loss function of involve organs, such as heat, pain redness, and swelling. Marine natural products have gained more and more attention due to their unique mechanism of anti-inflammatory action, and have considered a hotspot for anti-inflammatory drug development. Marine-derived fungi are promising sources of structurally unprecedented bioactive natural products. So far, a plethora of new secondary metabolites with anti-inflammatory activities from marine-derived fungi had been widely reported. This review covers 133 fungal metabolites described in the period of 2000 to 2018, including the structures and origins of these secondary metabolites.
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