Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 84, Issue 22, Pages 14760-14769Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b02347
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Funding
- NSFC [21632003, 21871116, 21572087, 21801102]
- key program of Gansu province [17ZD2GC011]
- 111 program from the MOE of P. R. China
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An efficient method was successfully developed to obtain cyclic beta-amino ketones via visible-light photoredox catalysis. With this catalytic system, vinyl azides and N-Ph pyrrolidines react to form cyclic beta-amino ketones by alpha-amino radical addition. This method provides a simple, mild, straightforward, and novel paradigm to prepare important beta-amino ketones.
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