Two novel mixed-ligand zinc-acesulfame compounds: Synthesis, spectroscopic and thermal characterization and biological applications

Two new tetrahedral acesulfame complexes, acesulfamato(N)acesulfamato(O)bis(3-aminopyridine) zinc(II) (C18H2ON6O8S2Zn, Zn-ace-3ap) and bis(acesulfamato-O)bis(benzotriazole)zinc(II) (C20H18N8O8S2Zn, Zn-ace-bta), were synthesized and characterized by single crystal X-ray diffraction, FT-IR spectroscopy, elemental analysis and thermal analysis techniques(TGA, DTA, DTG). The first compound, Zn-ace-3ap, crystallizes in triclinic space group P1 with parameters a = 7.978 (7) angstrom, b = 9.907 (6) angstrom, c = 15.778 (14) angstrom, alpha = 78.24 degrees (2), beta = 81.22 degrees (4), gamma = 75.99 degrees (2), Z = 2 and The second compound, Zn-ace-bta, crystallizes in monoclinic space group C2/c with parameters a = 19.879 (3) angstrom, b = 9.3637 (13) angstrom, c = 14.0852 (18) angstrom, beta = 105.483 degrees (4), Z = 4. The biological activities of the synthesized complexes were appraised through disk diffusion method as antibacterial, antimicrobial and antifungal in DMSO. Enterococcus faecalis (ATCC-29212), Staphylococcus aureus (ATCC-25923) as gram-positive bacteria, Pseudomonas aeroginosa (ATCC-27853) and Escherichia coli (ATCC-25922) as gram-negative bacteria, and Candida albicans (ATCC-10231) as fungus were grown with a view to investigate the antimicrobial effects of the complexes. (C) 2019 Elsevier B.V. All rights reserved.