Influence of degree of substitution on the host-guest inclusion complex between ionic liquid substituted β-cyclodextrins with 2,4-dichlorophenol: An electrochemical, NMR and molecular docking studies

A mono- and di-substituted ionic liquid-beta-cyclodextrin (beta-CD-ILs) were synthesized and their host-guest inclusion complex with 2, 4-dichlorophenol (2,4-DCP) were evaluated by electrochemical study. First, both beta-CD-ILs which is beta-CD-1-BIMOTs and beta-CD-2-BIMOTs were fabricated on carbon paste electrode (CPE) for determination of 2,4-DCP. The cyclic voltammetry results indicate that both beta-CD-IL/CPEs exhibit higher oxidation peak current compared to native beta-CD/CPE. Both complexes possess high sensitivity, stability and reproducibility. However, as the degree of substitution of ionic liquid (IL) increases, the selectivity of beta-CD-IL towards 2,4-DCP decreases. Thus, it can be deduced that the degree of substitution of IL is influencing the host-guest inclusion complex of beta-CD-ILs with 2,4-DCP. (C) 2019 Elsevier B.V. All rights reserved.