4.4 Article

MnSb2O6-chitosan nanocomposite: An efficient catalyst for the synthesis of coumarins via Pechmann reaction

Journal

JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 57, Issue 1, Pages 173-181

Publisher

WILEY
DOI: 10.1002/jhet.3763

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In this work, MnSb2O6-chitosan nanocomposites were synthesized and have been employed in Pechmann condensation for the synthesis of coumarin derivatives. MnSb2O6-chitosan nanocomposites were characterized by Fourier transform infrared (FTIR), X-ray powder diffraction (XRD), scanning electron microscope (SEM), and energy-dispersive X-ray spectroscopy (EDX) techniques. The particles of MnSb2O6-chitosan have uniform spheres with sizes that are less than 100 nm. Simplicity, easy work-up, and short reaction times are advantages of this reaction. Also, we evaluated the antibacterial activity for some of the products, and the result showed significant pharmaceutical activities as antibacterial reagents against Staphylococcus aureus and Escherichia coli.

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