Journal
JOURNAL OF DERMATOLOGY
Volume 46, Issue 12, Pages 1053-1101Publisher
WILEY
DOI: 10.1111/1346-8138.15090
Keywords
atopic dermatitis; clinical practice guidelines; clinical questions; evidence-based medicine; treatment
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Funding
- Ministry of Health, Labour and Welfare, Japan (as a Research Project on Measures for Intractable Diseases [Research on Allergic Disease and Immunology])
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Atopic dermatitis (AD) is a disease characterized by relapsing eczema with pruritus as a primary lesion. The current strategies to treat AD in Japan from the perspective of evidence-based medicine consist of three primary measures: (i) the use of topical corticosteroids and tacrolimus ointment as the main treatment for the inflammation; (ii) topical application of emollients to treat the cutaneous barrier dysfunction; and (iii) avoidance of apparent exacerbating factors, psychological counseling and advice about daily life. The guidelines present recommendations to review clinical research articles, evaluate the balance between the advantages and disadvantages of medical activities, and optimize medical activity-related patient outcomes with respect to several important points requiring decision-making in clinical practice.
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