Comparison of anterior segment and lens biometric measurements in patients with cataract

Purpose This study was performed to compare anterior ocular biometric measurements of deep-range swept-source anterior segment optical coherence tomography (AS-OCT) (CASIA2) versus short-range swept-source AS-OCT (CASIA SS-1000), ultrasonography (AL-4000), and Scheimpflug camera analysis (Pentacam and EAS-1000) in patients with cataract. Methods One hundred eighty-five eyes of 128 participants with mild refractive error or cataract were examined. The central corneal thickness (CCT), aqueous depth (AQD), and lens thickness were obtained. The repeatability of CASIA2 measurements was assessed. Results In patients with cataract, the CCT, AQD, lens thickness, and lens anterior curvature by CASIA2 showed high intraclass correlation coefficients (ICCs) of > 0.99. Conversely, measurements of the posterior part of the lens such as lens posterior curvature showed lower ICCs. The ICCs were higher in healthy young participants than in patients with cataract. The ICCs tended to be lower in patients with mild than dense cataract. There was no statistically significant difference in the CCT and AQD between the CASIA2 and CASIA SS-1000 or in the lens thickness measurements between the CASIA2 and AL-4000 and between the CASIA2 and EAS-1000. There was a significant linear correlation in the biometric measurements between the CASIA2 and the other instruments. Conclusion We evaluated the biometric measurements of the anterior eye segment by the CASIA2. The CASIA2 yielded results comparable with those of the CASIA SS-1000, ultrasonography, and Scheimpflug camera. However, mild cataract decreased the repeatability of measurements of the posterior part of the lens.