Journal
BIOMARKERS IN MEDICINE
Volume 10, Issue 12, Pages 1225-1229Publisher
FUTURE MEDICINE LTD
DOI: 10.2217/bmm-2016-0184
Keywords
biomarker; inflammation; N-acetylmuramoyl-L-alanine amidase; proteomics; sepsis
Categories
Ask authors/readers for more resources
Aim: Sepsis is a critical condition that leads to high mortality and is the most common cause of death in intensive care units. Despite exhaustive efforts by the scientific community, a reliable biomarker for diagnosis, evolution and prognosis of sepsis is still lacking. Results & methodology: Here, using high-throughput proteomics, we describe N-acetylmuramoyl-L-alanine amidase as a novel candidate for differentiating infectious and noninfectious inflammatory syndromes. Discussion & conclusion: This is the first description of N-acetylmuramoyl-L-alanine amidase as a biomarker that can be used alone or in conjunction with other biomarkers to facilitate the diagnosis of sepsis in the critically ill.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available