Journal
BIOMARKERS
Volume 21, Issue 4, Pages 347-352Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/1354750X.2016.1139183
Keywords
In vivo; portable; X-ray fluorescence
Categories
Funding
- National Institute for Occupational Safety and Health (NIOSH) R21 grant [1R21OH010044]
- National Natural Science Foundation of China [81373016, 30901205]
- National Basic Research Program of China (973'' Program) [2012CB525001]
- Shanghai Science and Technology Committee [124119a1400]
- Purdue Ross Fellowship
- Purdue US-China visiting scholar network travel grant program
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Childhood lead (Pb) poisoning remains a global issue, especially in industrial areas. In this study, 115 children with average age 5.7 years were recruited as either patient diagnosed with Pb poisoning or controls at Xinhua Hospital in China. The subjects' bone Pb was measured with a K-shell X-ray fluorescence (KXRF) and a portable X-ray fluorescence (XRF) system. A significant correlation between KXRF bone Pb and blood Pb and portable XRF and KXRF measurements were observed. The half-life of blood-lead was calculated to be 9.96 +/- 3.92 d. Our results indicate that bone is a useful biomarker for Pb in children.
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