Journal
EUROPEAN JOURNAL OF INTERNAL MEDICINE
Volume 71, Issue -, Pages 32-38Publisher
ELSEVIER
DOI: 10.1016/j.ejim.2019.10.026
Keywords
Aged; Atrial fibrillation; Direct oral anticoagulants; Frail elderly
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Direct Oral Anticoagulants (DOACs) consistently demonstrated a greater net clinical benefit compared to Vitamin K Antagonists (VKAs) also in persons aged 75 years and over, who account for the largest proportion of AF patients; however, major uncertainties in DOACs prescription have to do with this age group. In this review, persistent uncertainties and implications of frailty and geriatric syndromes on DOACs prescription, and practical use of DOACs in real-world older persons, and will be discussed.
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