Fe3O4@SiO2-PANI-Au Nanocomposite Prepared for Electrochemical Determination of Quercetin in Food Samples and Biological Fluids

A new electrochemical sensor based on Fe3O4@SiO2-PANI-Au nanocomposite was fabricated for modification of glassy carbon electrode (Fe3O4@SiO2-PANI-Au GCE). The Fe3O4@SiO2-PANI-Au nanocomposite was characterized by TEM, FESEM-EDS-Mapping, XRD, and TGA methods. The Fe3O4@SiO2-PANI-Au GC electrode exhibited an acceptable sensitivity, fast electrochemical response, and good selectivity for determination of quercetin. Under optimal conditions, the linear range for quercetin concentrations using this sensor was 1.0x10(-8) to 1.5x10(-5) mol L-1, and the limit of detection was 3.8x10(-9) mol L-1. The results illustrated that the offered sensor could be a possible alternative for the measurement of quercetin in food samples and biological fluids.