4.3 Review

Application of Palladium-Catalyzed Cross-Coupling Reactions in Organic Synthesis

Journal

CURRENT ORGANIC SYNTHESIS
Volume 16, Issue 8, Pages 1105-1142

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1570179416666191104093533

Keywords

Palladium catalyst; cross-coupling; Heck reaction; Suzuki-Miyaura; Stille; Sonogashira Coupling; Buchwald-Hartwig reaction; Ullmann reaction

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Palladium-catalyzed cross-coupling reactions have gained a continuously growing interest of synthetic organic chemists. The present review gives a brief account of applications of the palladium-catalyzed cross-coupling reactions in comprehensive synthesis, viz., the Heck, Stille, Suzuki-Miyaura, Negishi, Sonogashira, Buchwald-Hartwig, Ullmann and the Oxidative, decarboxylative cross-coupling reactions, with particular emphasis on the synthesis of heterocyclic compounds.

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