Journal
CURRENT OPINION IN IMMUNOLOGY
Volume 60, Issue -, Pages 96-102Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.coi.2019.05.008
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Funding
- National Institutes of Health [AI112640, AI118962, AI123124, AI36520, AI54959, BX02073]
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Reactive nitrogen species play diverse and essential roles in host pathogen interactions. Here, we review selected recent discoveries regarding nitric oxide (NO) in host defense and the pathogenesis of infection, mechanisms of bacterial NO resistance, production of NO by human macrophages, NO-based antimicrobial therapeutics and NO interactions with the gut microbiota.
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