Related references
Note: Only part of the references are listed.ARGONAUT-I: Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, against Gram-Negative Bacteria, Including Carbapenem-Resistant Nonfermenters and Enterobacteriaceae with Defined Extended-Spectrum β-Lactamases and Carbapenemases
Michael R. Jacobs et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2019)
Complexes formed by the siderophore-based monosulfactam antibiotic BAL30072 and their interaction with the outer membrane receptor PiuA of P-aeruginosa
Mariano Andrea Scorciapino et al.
BIOMETALS (2019)
Pharmacokinetics, Safety, and Tolerability Evaluation of Single and Multiple Doses of GSK3342830 in Healthy Volunteers
David Tenero et al.
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT (2019)
Pharmacodynamics of cefiderocol, a novel siderophore cephalosporin, in a Pseudomonas aeruginosa neutropenic murine thigh model
Islam M. Ghazi et al.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2018)
Humanized Exposures of Cefiderocol, a Siderophore Cephalosporin, Display Sustained in vivo Activity against Siderophore-Resistant Pseudomonas aeruginosa
Islam M. Ghazi et al.
PHARMACOLOGY (2018)
Cefiderocol versus imipenem-cilastatin for the treatment of complicated urinary tract infections caused by Gram-negative uropathogens: a phase 2, randomised, double-blind, non-inferiority trial
Simon Portsmouth et al.
LANCET INFECTIOUS DISEASES (2018)
1351. In vitro Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, Against Enterobacteriaceae With Defined Extended-Spectrum Β-Lactamases and Carbapenemases
Michael R Jacobs et al.
Open Forum Infectious Diseases (2018)
In Vitro Antibacterial Properties of Cefiderocol, a Novel Siderophore Cephalosporin, against Gram-Negative Bacteria
Akinobu Ito et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2018)
Activity of the novel siderophore cephalosporin cefiderocol against multidrug-resistant Gram-negative pathogens
J. Dobias et al.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2017)
Activity of cefiderocol (S-649266) against carbapenem-resistant Gram-negative bacteria collected from inpatients in Greek hospitals
Matthew E. Falagas et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2017)
What we may expect from novel antibacterial agents in the pipeline with respect to resistance and pharmacodynamic principles
Karen Bush et al.
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2017)
Coordination of Bactericidal and Iron Regulatory Functions of Hepcidin in Innate Antimicrobial Immunity in a Zebrafish Model
Xiao-feng Jiang et al.
SCIENTIFIC REPORTS (2017)
Efficacy of Humanized Exposures of Cefiderocol (S-649266) against a Diverse Population of Gram-Negative Bacteria in a Murine Thigh Infection Model
Marguerite L. Monogue et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
Efficacy of Cefiderocol against Carbapenem-Resistant Gram-Negative Bacilli in Immunocompetent-Rat Respiratory Tract Infection Models Recreating Human Plasma Pharmacokinetics
Shuhei Matsumoto et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
In Vitro Activity of the Siderophore Cephalosporin, Cefiderocol, against a Recent Collection of Clinically Relevant Gram-Negative Bacilli from North America and Europe, Including Carbapenem-Nonsusceptible Isolates (SIDERO-WT-2014 Study)
Meredith A. Hackel et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii
Lucile Moynie et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
In Vitro Antimicrobial Activity of a Siderophore Cephalosporin, S-649266, against Enterobacteriaceae Clinical Isolates, Including Carbapenem-Resistant Strains
Naoki Kohira et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Stability of Novel Siderophore Cephalosporin S-649266 against Clinically Relevant Carbapenemases
Tsukasa Ito-Horiyama et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Adaptive resistance to antibiotics in bacteria: a systems biology perspective
Santiago Sandoval-Motta et al.
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2016)
Structural basis for haem piracy from host haemopexin by Haemophilus influenzae
Silvia Zambolin et al.
NATURE COMMUNICATIONS (2016)
Bacterial ferrous iron transport: the Feo system
Cheryl K. Y. Lau et al.
FEMS MICROBIOLOGY REVIEWS (2016)
Coordination Chemistry of Microbial Iron Transport
Kenneth N. Raymond et al.
ACCOUNTS OF CHEMICAL RESEARCH (2015)
Pharmacodynamic Profiling of a Siderophore-Conjugated Monocarbam in Pseudomonas aeruginosa: Assessing the Risk for Resistance and Attenuated Efficacy
Aryun Kim et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
Potentiation of Antibacterial Activity of the MB-1 Siderophore-Monobactam Conjugate Using an Efflux Pump Inhibitor
Andrew P. Tomaras et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
Discovery of Efficacious Pseudomonas aeruginosa-Targeted Siderophore-Conjugated Monocarbams by Application of a Semi-mechanistic Pharmacokinetic/Pharmacodynamic Model
Kerry E. Murphy-Benenato et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3
Kerry E. Murphy-Benenato et al.
ACS MEDICINAL CHEMISTRY LETTERS (2015)
Adaptive Resistance in Bacteria Requires Epigenetic Inheritance, Genetic Noise, and Cost of Efflux Pumps
Santiago Sandoval Motta et al.
PLOS ONE (2015)
Iron homeostasis in host defence and inflammation
Tomas Ganz et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Heme uptake in bacterial pathogens
Heidi Contreras et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2014)
Adaptation of Iron Homeostasis Pathways by a Pseudomonas aeruginosa Pyoverdine Mutant in the Cystic Fibrosis Lung
Angela T. Nguyen et al.
JOURNAL OF BACTERIOLOGY (2014)
Coordinated Rearrangements between Cytoplasmic and Periplasmic Domains of the Membrane Protein Complex ExbB-ExbD of Escherichia coli
Aleksandr Sverzhinsky et al.
STRUCTURE (2014)
Siderocalin Outwits the Coordination Chemistry of Vibriobactin, a Siderophore of Vibrio cholerae
Benjamin E. Allred et al.
ACS CHEMICAL BIOLOGY (2013)
Siderophore conjugates
Malcolm G. P. Page
ANTIMICROBIAL THERAPEUTICS REVIEWS: THE BACTERIAL CELL WALL AS AN ANTIMICROBIAL TARGET (2013)
Involvement of Fe Uptake Systems and AmpC β-Lactamase in Susceptibility to the Siderophore Monosulfactam BAL30072 in Pseudomonas aeruginosa
Christian van Delden et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
Adaptation-Based Resistance to Siderophore-Conjugated Antibacterial Agents by Pseudomonas aeruginosa
Andrew P. Tomaras et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
Siderocalins: Siderophore binding proteins evolved for primary pathogen host defense
Allyson K. Sia et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2013)
Iron deficiency and susceptibility to infections: evaluation of the clinical evidence
G. S. Tansarli et al.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2013)
Pyridone-Conjugated Monobactam Antibiotics with Gram-Negative Activity
Matthew F. Brown et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Pseudomonas aeruginosa adapts its iron uptake strategies in function of the type of infections
Pierre Cornelis et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2013)
Iron, copper, zinc, and manganese transport and regulation in pathogenic Enterobacteria: correlations between strains, site of infection and the relative importance of the different metal transport systems for virulence
Gaëlle Porcheron et al.
Frontiers in Cellular and Infection Microbiology (2013)
Biosynthesis of Albomycin δ2 Provides a Template for Assembling Siderophore and Aminoacyl-tRNA Synthetase Inhibitor Conjugates
Yu Zeng et al.
ACS CHEMICAL BIOLOGY (2012)
Clinically Relevant Gram-Negative Resistance Mechanisms Have No Effect on the Efficacy of MC-1, a Novel Siderophore-Conjugated Monocarbam
Craig J. McPherson et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
NGAL-Siderocalin in kidney disease
Neal Paragas et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
Characterization of the aqueous iron(III) chelation chemistry of a potential Trojan Horse antimicrobial agent: chelate structure, stability and pH dependent speciation
James M. Harrington et al.
BIOMETALS (2012)
Chemical syntheses and in vitro antibacterial activity of two desferrioxamine B-ciprofloxacin conjugates with potential esterase and phosphatase triggered drug release linkers
Cheng Ji et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Mammalian Siderophores, Siderophore-binding Lipocalins, and the Labile Iron Pool
Colin Correnti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Immune Interference in Mycobacterium tuberculosis Intracellular Iron Acquisition through Siderocalin Recognition of Carboxymycobactins
Trisha M. Hoette et al.
ACS CHEMICAL BIOLOGY (2011)
Mechanism of Bactericidal Activity of Microcin L in Escherichia coli and Salmonella enterica
Natacha Morin et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2011)
In vitro activity of BAL30072 against Burkholderia pseudomallei
Takehiko Mima et al.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2011)
Adaptive resistance to cationic compounds in Pseudomonas aeruginosa
Anna Skiada et al.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2011)
Distinctive Attributes of β-Lactam Target Proteins in Acinetobacter baumannii Relevant to Development of New Antibiotics
Seungil Han et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Iron Homeostasis and the Inflammatory Response
Marianne Wessling-Resnick
ANNUAL REVIEW OF NUTRITION, VOL 30 (2010)
Isolation and Characterization of Two Members of the Siderophore-Microcin Family, Microcins M and H47
Gaelle Vassiliadis et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Adaptive Resistance to the Last Hope Antibiotics Polymyxin B and Colistin in Pseudomonas aeruginosa Is Mediated by the Novel Two-Component Regulatory System ParR-ParS
Lucia Fernandez et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
In Vitro Properties of BAL30072, a Novel Siderophore Sulfactam with Activity against Multiresistant Gram-Negative Bacilli
Malcolm G. P. Page et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Siderophore uptake in bacteria and the battle for iron with the host; a bird's eye view
Byron C. Chu et al.
BIOMETALS (2010)
The struggle for iron - a metal at the host-pathogen interface
Manfred Nairz et al.
CELLULAR MICROBIOLOGY (2010)
THE ROLE OF IRON AND CHELATORS ON INFECTIONS IN IRON OVERLOAD AND NON IRON LOADED CONDITIONS: PROSPECTS FOR THE DESIGN OF NEW ANTIMICROBIAL THERAPIES
George J. Kontoghiorghes et al.
HEMOGLOBIN (2010)
Chemistry and biology of siderophores
Robert C. Hider et al.
NATURAL PRODUCT REPORTS (2010)
Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa
Seungil Han et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Bacterial heme-transport proteins and their heme-coordination modes
Yong Tong et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2009)
Siderophores as drug delivery agents: application of the Trojan Horse strategy
Ute Moellmann et al.
BIOMETALS (2009)
Sideromycins: tools and antibiotics
Volkmar Braun et al.
BIOMETALS (2009)
Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex
Stefanie Krieg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Investigations of the MceIJ-catalyzed posttranslational modification of the microcin E492 C-terminus: Linkage of ribosomal and nonribosomal peptides to form Trojan Horse antibiotics
Elizabeth M. Nolan et al.
BIOCHEMISTRY (2008)
The siderocalin/enterobactin interaction: A link between mammalian immunity and bacterial iron transport
Rebecca J. Abergel et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Special conditions allow binding of the siderophore salmochelin to siderocalin (NGAL-lipocalin)
Marianne Valdebenito et al.
FEMS MICROBIOLOGY LETTERS (2007)
Parasitism of iron-siderophore receptors of Escherichia coli by the siderophore-peptide microcin E492m and its unmodified counterpart
Delphine Destoumieux-Garzon et al.
BIOMETALS (2006)
How pathogenic bacteria evade mammalian sabotage in the battle for iron
MA Fischbach et al.
NATURE CHEMICAL BIOLOGY (2006)
Iron-withholding strategy in innate immunity
Sek Tong Ong et al.
IMMUNOBIOLOGY (2006)
Iron and microbial infection
ME Schaible et al.
NATURE REVIEWS MICROBIOLOGY (2004)
Bacterial iron sources: From siderophores to hemophores
C Wandersman et al.
ANNUAL REVIEW OF MICROBIOLOGY (2004)
Lactoferrin receptors in Gram-negative bacteria: Insights into the iron acquisition process
A Ekins et al.
BIOMETALS (2004)
Lactoferrin - a multifunctional protein with antimicrobial properties
S Farnaud et al.
MOLECULAR IMMUNOLOGY (2003)
Salmochelins, siderophores of Salmonella enterica and uropathogenic Escherichia coli strains, are recognized by the outer membrane receptor IroN
K Hantke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Total iron-binding capacity calculated from serum transferrin concentration or serum iron concentration and unsaturated iron-binding capacity
H Yamanishi et al.
CLINICAL CHEMISTRY (2003)
Total iron binding capacity and transferrin concentration in the assessment of iron status
I Kasvosve et al.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2002)
Characterization of HasB, a Serratia marcescens TonB-like protein specifically involved in the haemophore-dependent haem acquisition system
A Paquelin et al.
MOLECULAR MICROBIOLOGY (2001)
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
CH Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Effect of conalbumin on the activity of Syn 2190, a 1,5 dihydroxy-4-pyridon monobactam inhibitor of AmpC beta-lactamases
GS Babini et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2000)
Share Paper
