Journal
CHEMISTRY OF HETEROCYCLIC COMPOUNDS
Volume 55, Issue 9, Pages 851-855Publisher
SPRINGER
DOI: 10.1007/s10593-019-02548-9
Keywords
aldehydes; imidazo[4,5-b]pyridine-2,5(4H,6H)-diones; 4-imino-1-phenylimidazolidin-2-one; Meldrum's acid; 5-substituted 1-phenylhydantoins; three-component condensation
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A convenient method for the synthesis of previously unknown imidazo[4,5-b]pyridine-2,5(4H,6H)-diones has been developed, based on a three-component condensation of 4-imino-1-phenylimidazolidin-2-one with aldehydes and Meldrum's acid. The possibility of accessing 5-substituted 1-phenylhydantoins based on the acid hydrolysis of imidazo[4,5-b]pyridine-2,5(4H,6H)-diones was shown.
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