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Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice
Alexander Pfeifer et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Bace1 modulates myelination in the central and peripheral nervous system
Xiangyou Hu et al.
NATURE NEUROSCIENCE (2006)
Oxidation, glycoxidation, lipoxidation, nitration, and responses to oxidative stress in the cerebral cortex in Creutzfeldt-Jakob disease
M. Freixes et al.
NEUROBIOLOGY OF AGING (2006)
A key role for the microglial NADPH oxidase in APP-dependent killing of neurons
Bin Qin et al.
NEUROBIOLOGY OF AGING (2006)
Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1α transcription and mitochondrial biogenesis in muscle cells
Zhidan Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The 37-kDa/67-kDa laminin receptor acts as a receptor for infectious prions and is inhibited by polysulfated glycanes
Sabine Gauczynski et al.
JOURNAL OF INFECTIOUS DISEASES (2006)
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction
Latha Devi et al.
JOURNAL OF NEUROSCIENCE (2006)
Cell-permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis
Susanne Petri et al.
JOURNAL OF NEUROCHEMISTRY (2006)
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3) K-Akt signalling
Lara Fallon et al.
NATURE CELL BIOLOGY (2006)
Suppression of prion protein in livestock by RNA interference
MC Golding et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Interface between tauopathies and synucleinopathies: A tale of two proteins
WR Galpern et al.
ANNALS OF NEUROLOGY (2006)
Risk factors for variant Creutzfeldt-Jakob disease: A case-control study
HJT Ward et al.
ANNALS OF NEUROLOGY (2006)
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
F Liu et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice
D Dominguez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Redox metals and oxidative abnormalities in human prion diseases
RB Petersen et al.
ACTA NEUROPATHOLOGICA (2005)
Pseudo-phosphorylation of tau at Ser202 and Thr205 affects tau filament formation
CA Rankin et al.
MOLECULAR BRAIN RESEARCH (2005)
β subunits of voltage-gated sodium channels are novel substrates of β-site amyloid precursor protein-cleaving enzyme (BACE1) and γ-secretase
HK Wong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Rasagiline as an adjunct to levodopa in patients with Parkinson's disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): a randomised, double-blind, parallel-group trial
O Rascol et al.
LANCET (2005)
Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells
M Pickhardt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor
JT Slevin et al.
JOURNAL OF NEUROSURGERY (2005)
Glial cell line-derived neurotrophic factor mediates the desirable actions of the anti-addiction drug ibogaine against alcohol consumption
DY He et al.
JOURNAL OF NEUROSCIENCE (2005)
Tau pathology in Alzheimer disease and other tauopathies
K Iqbal et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)
Modulation of neurodegeneration by molecular chaperones
PJ Muchowski et al.
NATURE REVIEWS NEUROSCIENCE (2005)
Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation
H Kadowaki et al.
CELL DEATH AND DIFFERENTIATION (2005)
HSP27 but not HSP70 has a potent protective effect against α-synuclein-induced cell death in mammalian neuronal cells
A Zourlidou et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Knock-down of the 37-kDa/67-kDa laminin receptor in mouse brain by transgenic expression of specific antisense LRP RNA
C Leucht et al.
TRANSGENIC RESEARCH (2004)
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
AM Cuervo et al.
SCIENCE (2004)
Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient
AH Peden et al.
LANCET (2004)
An antiaggregation gene therapy strategy for Lewy body disease utilizing β-synuclein lentivirus in a transgenic model
M Hashimoto et al.
GENE THERAPY (2004)
How does parkin ligate ubiquitin to Parkinson's disease? First in molecular medicine review series
PJ Kahle et al.
EMBO REPORTS (2004)
Hsp70 reduces α-synuclein aggregation and toxicity
J Klucken et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The importance of neuritic plaques and tangles to the development and evolution of AD
P Tiraboschi et al.
NEUROLOGY (2004)
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
EM Valente et al.
SCIENCE (2004)
Scrapie-Infected Mice and PrP Knockout Mice Share Abnormal Localization and Activity of Neuronal Nitric Oxide Synthase
Gilmor I. Keshet et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Adenosine A2A receptor antagonist treatment of Parkinson's disease
W Bara-Jimenez et al.
NEUROLOGY (2003)
Efficient and specific down-regulation of prion protein expression by RNAi
G Tilly et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
SS Gill et al.
NATURE MEDICINE (2003)
Colocalization of tau and alpha-synuclein epitopes in Lewy bodies
T Ishizawa et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2003)
Tremor in Parkinson's disease and serotonergic dysfunction -: An 11C-WAY 100635 PET study
M Doder et al.
NEUROLOGY (2003)
Acquired prion disease: iatrogenic CJD, variant CJD, kuru
RG Will
BRITISH MEDICAL BULLETIN (2003)
XIB4035, a novel nonpeptidyl small molecule agonist for GFR alpha-1
K Tokugawa et al.
NEUROCHEMISTRY INTERNATIONAL (2003)
Microglia enhance β-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species
LY Qin et al.
JOURNAL OF NEUROCHEMISTRY (2002)
TorsinA and heat shock proteins act as molecular chaperones:: suppression of α-synuclein aggregation
PJ McLean et al.
JOURNAL OF NEUROCHEMISTRY (2002)
A pilot study of the manual force levels required to produce manipulation induced hypoalgesia
S McLean et al.
CLINICAL BIOMECHANICS (2002)
Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model
JC Dodart et al.
NATURE NEUROSCIENCE (2002)
Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease
PK Auluck et al.
SCIENCE (2002)
CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils
IS Coraci et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease
RB DeMattos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Neuroprotection by caffeine and A2A adenosine receptor inactivation in a model of Parkinson's disease
JF Chen et al.
JOURNAL OF NEUROSCIENCE (2001)
The molecular biology of prion propagation
AR Clarke et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES (2001)
Inhibitory role for dual specificity phosphatase VHR in T cell antigen receptor and CD28-induced Erk and Jnk activation
A Alonso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
H Shimura et al.
NATURE GENETICS (2000)
Neuroprotection, excitotoxicity and NMDA antagonists
RJ Gagliardi
ARQUIVOS DE NEURO-PSIQUIATRIA (2000)