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JOURNAL OF CLINICAL INVESTIGATION (2007)
Tau interacts with Golgi membranes and mediates their association with microtubules
Carole Abi Farah et al.
CELL MOTILITY AND THE CYTOSKELETON (2006)
Folding of the repeat domain of tau upon binding to lipid surfaces
Patrick Barre et al.
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Estrogen dissociates Tau and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor subunit in postischemic hippocampus
Gloria Patricia Cardona-Gomez et al.
NEUROREPORT (2006)
Exosomes are released by cultured cortical neurones
J Fauré et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2006)
The proline-rich domain and the microtubule binding domain of protein Tau acting as RNA binding domains
XingShen Wang et al.
PROTEIN AND PEPTIDE LETTERS (2006)
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
F Liu et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Parkinsonism-dementia complex of Guam
JC Steele
MOVEMENT DISORDERS (2005)
Dimeric amyloid β protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease
T Kawarabayashi et al.
JOURNAL OF NEUROSCIENCE (2004)
Nanotubular highways for intercellular organelle transport
A Rustom et al.
SCIENCE (2004)
Template-assisted filament growth by parallel stacking of tau
M Margittai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Argyrophilic grain disease: A late-onset dementia with distinctive features among tauopathies
M Tolnay et al.
NEUROPATHOLOGY (2004)
Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy
B Zhang et al.
JOURNAL OF NEUROSCIENCE (2004)
Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals
T Arendt et al.
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Anionic micelles and vesicles induce tau fibrillization in vitro
CN Chirita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Initiation and synergistic fibrillization of tau and alpha-synuclein
BI Giasson et al.
SCIENCE (2003)
Colocalization of tau and alpha-synuclein epitopes in Lewy bodies
T Ishizawa et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2003)
Chaperones increase association of tau protein with microtubules
F Dou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease
S Oddo et al.
NEUROBIOLOGY OF AGING (2003)
Single-molecule investigation of the interference between kinesin, tau and MAP2c
A Seitz et al.
EMBO JOURNAL (2002)
Annular α-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes
TT Ding et al.
BIOCHEMISTRY (2002)
Process outgrowth of oligodendrocytes is promoted by interaction of Fyn kinase with the cytoskeletal protein Tau
C Klein et al.
JOURNAL OF NEUROSCIENCE (2002)
Formation of neurofibrillary tangles in P301L tau transgenic mice induced by Aβ42 fibrils
J Götz et al.
SCIENCE (2001)
Nucleated conformational conversion and the replication of conformational information by a prion determinant
TR Serio et al.
SCIENCE (2000)
NACP/α-synuclein and tau constitute two distinctive subsets of filaments in the same neuronal inclusions in brains from a family of parkinsonism and dementia with Lewy bodies:: double-immunolabeling fluorescence and electron microscopic studies
K Arima et al.
ACTA NEUROPATHOLOGICA (2000)
Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments
T Maas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming β structure
M von Bergen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Differential assembly of human tau isoforms in the presence of arachidonic acid
ME King et al.
JOURNAL OF NEUROCHEMISTRY (2000)
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