Related references
Note: Only part of the references are listed.Quantitative systems pharmacology of interferon alpha administration: A multi-scale approach
Priyata Kalra et al.
PLOS ONE (2019)
In silico comparison of protein-bound uremic toxin removal by hemodialysis, hemodiafiltration, membrane adsorption, and binding competition
Vaibhav Maheshwari et al.
SCIENTIFIC REPORTS (2019)
A Cell-Level Systems PK-PD Model to Characterize In Vivo Efficacy of ADCs
Aman P. Singh et al.
PHARMACEUTICS (2019)
Tuberculosis drugs' distribution and emergence of resistance in patient's lung lesions: A mechanistic model and tool for regimen and dose optimization
Natasha Strydom et al.
PLOS MEDICINE (2019)
Inoculum effect of β-lactam antibiotics
Justin R. Lenhard et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2019)
In vitro and in silico analysis of the effects of D-2 receptor antagonist target binding kinetics on the cellular response to fluctuating dopamine concentrations
Wilhelmus E. A. de Witte et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
Drug-Target Kinetics in Drug Discovery
Peter J. Tonge
ACS CHEMICAL NEUROSCIENCE (2018)
Using Chemical Reaction Kinetics to Predict Optimal Antibiotic Treatment Strategies
Pia Abel zur Wiesch et al.
PLOS COMPUTATIONAL BIOLOGY (2017)
Modeling the Kinetics of the Permeation of Antibacterial Agents into Growing Bacteria and Its Interplay with Efflux
Wright W. Nichols
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
The drug-target residence time model: a 10-year retrospective
Robert A. Copeland
NATURE REVIEWS DRUG DISCOVERY (2016)
Antimicrobial combinations: Bliss independence and Loewe additivity derived from mechanistic multi-hit models
Desiree Y. Baeder et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2016)
Translating slow-binding inhibition kinetics into cellular and in vivo effects
Grant K. Walkup et al.
NATURE CHEMICAL BIOLOGY (2015)
Classic reaction kinetics can explain complex patterns of antibiotic action
Pia Abel zur Wiesch et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Characterization of plasma protein binding dissociation with online SPE-HPLC
Ping Li et al.
SCIENTIFIC REPORTS (2015)
A comprehensive analysis of the influence of drug binding kinetics on drug action at molecular and systems levels
Ning Yin et al.
MOLECULAR BIOSYSTEMS (2013)
Virus Neutralisation: New Insights from Kinetic Neutralisation Curves
Carsten Magnus
PLOS COMPUTATIONAL BIOLOGY (2013)
The Hill equation and the origin of quantitative pharmacology
Rudolf Gesztelyi et al.
ARCHIVE FOR HISTORY OF EXACT SCIENCES (2012)
Mechanism-based population pharmacokinetic modelling in diabetes: vildagliptin as a tight binding inhibitor and substrate of dipeptidyl peptidase IV
Cornelia B. Landersdorfer et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2012)
Analysis of the Subunit Stoichiometries in Viral Entry
Carsten Magnus et al.
PLOS ONE (2012)
Restricted occupancy models for neutralization of HIV virions and populations
Carsten Magnus et al.
JOURNAL OF THEORETICAL BIOLOGY (2011)
A Critical Subset Model Provides a Conceptual Basis for the High Antiviral Activity of Major HIV Drugs
Lin Shen et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Functional relationship between bacterial cell density and the efficacy of antibiotics
Klas I. Udekwu et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2009)
Population pharmacodynamic modelling of aspirin- and ibuprofen-induced inhibition of platelet aggregation in healthy subjects
Ying Hong et al.
CLINICAL PHARMACOKINETICS (2008)
Animal-to-human extrapolation of the pharmacokinetic and pharmacodynamic properties of buprenorphine
Ashraf Yassen et al.
CLINICAL PHARMACOKINETICS (2007)
Opinion - Drug-target residence time and its implications for lead optimization
Robert A. Copeland et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Pharmacokinetic-pharmacodynamic modelling: History and perspectives
Chantal Csajka et al.
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2006)
Diversity of mechanism-based pharmacodynamic models
DE Mager et al.
DRUG METABOLISM AND DISPOSITION (2003)
Gastric acid secretion in the dog:: A mechanism-based pharmacodynamic model for histamine stimulation and irreversible inhibition by omeprazole
A Äbelö et al.
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2002)
Determination of drug-plasma protein binding kinetics and equilibria by chromatographic profiling: Exemplification of the method using L-tryptophan and albumin
AM Talbert et al.
ANALYTICAL CHEMISTRY (2002)
General pharmacokinetic model for drugs exhibiting target-mediated drug disposition
DE Mager et al.
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2001)