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CURRENT OPINION IN CELL BIOLOGY (2007)
Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break
Benjamin P. C. Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Gene expression of ERCC1 as a novel prognostic marker in advanced bladder cancer patients receiving cisplatin-based chemotherapy
J. Bellmunt et al.
ANNALS OF ONCOLOGY (2007)
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
Yeshayahu Schlesinger et al.
NATURE GENETICS (2007)
Epigenetic inactivation of the chromosomal stability control genes BRCA1, BRCA2, and XRCC5 in non-small cell lung cancer
Ming-Ni Lee et al.
CLINICAL CANCER RESEARCH (2007)
Different structural states in oligonucleosomes are required for early versus late steps of base excision repair
Shima Nakanishi et al.
NUCLEIC ACIDS RESEARCH (2007)
ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling
Thomas Stiff et al.
EMBO JOURNAL (2006)
PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
Minli Wang et al.
NUCLEIC ACIDS RESEARCH (2006)
DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy
Ken A. Olaussen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
DNA repair pathways in clinical practice: Lessons from pediatric cancer susceptibility syndromes
Richard D. Kennedy et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex
KE Adams et al.
ONCOGENE (2006)
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
MJ Kruhlak et al.
JOURNAL OF CELL BIOLOGY (2006)
Promoter hypermethylation of FANCF plays an important role in the occurrence of ovarian cancer through disrupting Fanconi anemia-BRCA pathway
ZH Wang et al.
CANCER BIOLOGY & THERAPY (2006)
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.
C Stresemann et al.
CANCER RESEARCH (2006)
ATM regulates ATR chromatin loading in response to DNA double-strand breaks
M Cuadrado et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
The Polycomb group protein EZH2 directly controls DNA methylation
E Viré et al.
NATURE (2006)
Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells
JP Wittschieben et al.
CANCER RESEARCH (2006)
Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks
R Murr et al.
NATURE CELL BIOLOGY (2006)
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
A Jazayeri et al.
NATURE CELL BIOLOGY (2006)
The Polycomb group protein EZH2 impairs DNA repair in breast epithelial cells
M Zeidler et al.
NEOPLASIA (2005)
ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1
ZS You et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal
K Ghoshal et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/WAF1 expression, independent of histone deacetylase 1
BH Huang et al.
CELL DEATH AND DIFFERENTIATION (2005)
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
J Falck et al.
NATURE (2005)
Cell death by mitotic catastrophe: a molecular definition
M Castedo et al.
ONCOGENE (2004)
Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1
CY Gui et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival
CJ Marsit et al.
ONCOGENE (2004)
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
E Hernando et al.
NATURE (2004)
DNA damage-induced activation of ATM and ATM-dependent signaling pathways
EU Kurz et al.
DNA REPAIR (2004)
Interplay between chromatin and cell cycle checkpoints in the context of ATR/ATM-dependent checkpoints
S Koundrioukoff et al.
DNA REPAIR (2004)
Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites
JA Downs et al.
MOLECULAR CELL (2004)
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions
T Kusch et al.
SCIENCE (2004)
The ATM gene is a target for epigenetic silencing in locally advanced breast cancer
QN Vo et al.
ONCOGENE (2004)
ATR and ATM regulate the timing of DNA replication origin firing
D Shechter et al.
NATURE CELL BIOLOGY (2004)
The acquisition of hMLH1 methylation in plasma DNA after chemotherapy predicts poor survival for ovarian cancer patients
G Gifford et al.
CLINICAL CANCER RESEARCH (2004)
Ataxia-telangiectasia-mutated (ATM) gene in head and neck squamous cell carcinoma: Promoter hypermethylation with clinical correlation in 100 cases
LB Ai et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2004)
Hallmarks of 'BRCAness' in sporadic cancers
N Turner et al.
NATURE REVIEWS CANCER (2004)
Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells
RS Bindra et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Regulating mammalian checkpoints through Cdc25 inactivation
M Donzelli et al.
EMBO REPORTS (2003)
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
A Celeste et al.
NATURE CELL BIOLOGY (2003)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
L Zou et al.
SCIENCE (2003)
Chromatin remodeling activities act on UV-damaged nucleosomes and modulate DNA damage accessibility to photolyase
H Gaillard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
ATM and related protein kinases: Safeguarding genome integrity
Y Shiloh
NATURE REVIEWS CANCER (2003)
AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol
S Anand et al.
CANCER CELL (2003)
Frameshifts and deletions during in vitro translesion synthesis past Pt-DNA adducts by DNA polymerases β and η
E Bassett et al.
DNA REPAIR (2002)
The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle
R Hara et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
DC Schultz et al.
GENES & DEVELOPMENT (2002)
ATM gene inactivation in mantle cell lymphoma mainly occurs by truncating mutations and missense mutations involving the phosphatidylinositol-3 kinase domain and is associated with increasing numbers of chromosomal imbalances
E Camacho et al.
BLOOD (2002)
ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy
Y Shirota et al.
JOURNAL OF CLINICAL ONCOLOGY (2001)
Mammalian G1- and S-phase checkpoints in response to DNA damage
J Bartek et al.
CURRENT OPINION IN CELL BIOLOGY (2001)
ATR and ATRIP: Partners in checkpoint signaling
D Cortez et al.
SCIENCE (2001)
COMPASS: A complex of proteins associated with a trithorax-related SET domain protein
T Miller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Chromosome segregation and cancer: Cutting through the mystery
PV Jallepalli et al.
NATURE REVIEWS CANCER (2001)
Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences
A Tutt et al.
EMBO JOURNAL (2001)
Ataxia telangiectasia gene mutations in leukaemia and lymphoma
J Boultwood
JOURNAL OF CLINICAL PATHOLOGY (2001)
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