4.5 Review

Experimental identification of cancer driver alterations in the era of pan-cancer genomics

Related references

Note: Only part of the references are listed.
Article Cell & Tissue Engineering

Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids

Benedetta Artegiani et al.

CELL STEM CELL (2019)

Article Multidisciplinary Sciences

Age-related remodelling of oesophageal epithelia by mutated cancer drivers

Akira Yokoyama et al.

NATURE (2019)

Review Oncology

Roadmap for investigating epigenome deregulation and environmental origins of cancer

Zdenko Herceg et al.

INTERNATIONAL JOURNAL OF CANCER (2018)

Article Oncology

Systematic Functional Annotation of Somatic Mutations in Cancer

Patrick Kwok-Shing Ng et al.

CANCER CELL (2018)

Article Gastroenterology & Hepatology

Mutational landscape of a chemically-induced mouse model of liver cancer

Frances Connor et al.

JOURNAL OF HEPATOLOGY (2018)

Correction Biochemistry & Molecular Biology

Comprehensive Characterization of Cancer Driver Genes and Mutations (vol 173, 371.e1, 2018)

Matthew H. Bailey et al.

Article Multidisciplinary Sciences

Somatic mutant clones colonize the human esophagus with age

Inigo Martincorena et al.

SCIENCE (2018)

Article Biotechnology & Applied Microbiology

Chromatin loop anchors are associated with genome instability in cancer and recombination hotspots in the germline

Vera B. Kaiser et al.

GENOME BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors

Mi Ni Huang et al.

GENOME RESEARCH (2017)

Article Biochemistry & Molecular Biology

Carcinogen susceptibility is regulated by genome architecture and predicts cancer mutagenesis

Pablo E. Garcia-Nieto et al.

EMBO JOURNAL (2017)

Article Oncology

High-throughput Phenotyping of Lung Cancer Somatic Mutations

Alice H. Berger et al.

CANCER CELL (2016)

Article Multidisciplinary Sciences

Tissue-specific mutation accumulation in human adult stem cells during life

Francis Blokzijl et al.

NATURE (2016)

Article Cell Biology

Epigenetic Determinants of Cancer

Stephen B. Baylin et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)

Article Biotechnology & Applied Microbiology

OncodriveFML: a general framework to identify coding and non-coding regions with cancer driver mutations

Loris Mularoni et al.

GENOME BIOLOGY (2016)

Article Multidisciplinary Sciences

Sequential cancer mutations in cultured human intestinal stem cells

Jarno Drost et al.

NATURE (2015)

Article Multidisciplinary Sciences

Cell-of-origin chromatin organization shapes the mutational landscape of cancer

Paz Polak et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers

Melissa Q. McCreery et al.

NATURE MEDICINE (2015)

Article Biochemical Research Methods

Pathway and network analysis of cancer genomes

Pau Creixell et al.

NATURE METHODS (2015)

Article Multidisciplinary Sciences

High burden and pervasive positive selection of somatic mutations in normal human skin

Inigo Martincorena et al.

SCIENCE (2015)

Article Multidisciplinary Sciences

The mutational landscapes of genetic and chemical models of Kras-driven lung cancer

Peter M. K. Westcott et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition

Yoav D. Shaul et al.

Article Biotechnology & Applied Microbiology

Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal human mammary epithelial cells

Paul L. Severson et al.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2014)

Article Multidisciplinary Sciences

Modelling mutational landscapes of human cancers in vitro

Magali Olivier et al.

SCIENTIFIC REPORTS (2014)

Article Biochemistry & Molecular Biology

SWI/SNF Chromatin-Remodeling Factor Smarcd3/Baf60c Controls Epithelial-Mesenchymal Transition by Inducing Wnt5a Signaling

Nicole Vincent Jordan et al.

MOLECULAR AND CELLULAR BIOLOGY (2013)

Article Multidisciplinary Sciences

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Michael S. Lawrence et al.

NATURE (2013)

Article Cell Biology

Senescent cells harbour features of the cancer epigenome

Hazel A. Cruickshanks et al.

NATURE CELL BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization

Stella Tommasi et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Multidisciplinary Sciences

The Spectrum of SWI/SNF Mutations, Ubiquitous in Human Cancers

A. Hunter Shain et al.

PLOS ONE (2013)

Review Multidisciplinary Sciences

Cancer Genome Landscapes

Bert Vogelstein et al.

SCIENCE (2013)

Article Cell Biology

Genome-Wide Mutational Signatures of Aristolochic Acid and Its Application as a Screening Tool

Song Ling Poon et al.

SCIENCE TRANSLATIONAL MEDICINE (2013)

Article Multidisciplinary Sciences

Chromatin organization is a major influence on regional mutation rates in human cancer cells

Benjamin Schuster-Boeckler et al.

NATURE (2012)

Article Cell Biology

How to become immortal: let MEFs count the ways

Adam Odell et al.

AGING-US (2010)

Article Cell Biology

A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration

Gromoslaw A. Smolen et al.

GENES & DEVELOPMENT (2010)

Article Biochemistry & Molecular Biology

Wild-type and Hupki (Human p53 Knock-in) Murine Embryonic Fibroblasts p53/ARF PATHWAY DISRUPTION IN SPONTANEOUS ESCAPE FROM SENESCENCE

Catherine Whibley et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Biotechnology & Applied Microbiology

Epigenetic drivers and genetic passengers on the road to cancer

Carla Sawan et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2008)

Article Biochemistry & Molecular Biology

Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72

M. Reinbold et al.

ONCOGENE (2008)

Review Oncology

A census of human cancer genes

PA Futreal et al.

NATURE REVIEWS CANCER (2004)

Article Biotechnology & Applied Microbiology

p53 mutational spectra and the role of methylated CpG sequences

GP Pfeifer

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2000)