4.7 Article

DAPAR & ProStaR: software to perform statistical analyses in quantitative discovery proteomics

Journal

BIOINFORMATICS
Volume 33, Issue 1, Pages 135-136

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btw580

Keywords

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Funding

  1. EU FP7 program (Prime-XS Project) [262067]
  2. Prospectom project
  3. BBSRC Strategic Longer [BB/L002817/1]
  4. [ANR-2010-GENOM-BTV-002-01]
  5. [ANR-10-INBS-08]
  6. BBSRC [BB/L002817/1] Funding Source: UKRI
  7. Biotechnology and Biological Sciences Research Council [BB/L002817/1] Funding Source: researchfish

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DAPAR and ProStaR are software tools to perform the statistical analysis of label-free XIC-based quantitative discovery proteomics experiments. DAPAR contains procedures to filter, normalize, impute missing value, aggregate peptide intensities, perform null hypothesis significance tests and select the most likely differentially abundant proteins with a corresponding false discovery rate. ProStaR is a graphical user interface that allows friendly access to the DAPAR functionalities through a web browser.

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