Journal
BIOINFORMATICS
Volume 32, Issue 18, Pages 2853-2855Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btw315
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Funding
- National Science Foundation [NSF DMS 1160360]
- Division Of Mathematical Sciences
- Direct For Mathematical & Physical Scien [1160360] Funding Source: National Science Foundation
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Protein-nucleic acid interactions are among the most important intermolecular interactions in the regulation of cellular events. Identifying residues involved in these interactions from protein structure alone is an important challenge. Here we introduce the webserver interface to DNA Binding Site Identifier (DBSI), a powerful structure-based SVM model for the prediction and visualization of DNA binding sites on protein structures. DBSI has been shown to be a top-performing model to predict DNA binding sites on the surface of a protein or peptide and shows promise in predicting RNA binding sites.
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