4.7 Article

Coala: an R framework for coalescent simulation

Journal

BIOINFORMATICS
Volume 32, Issue 12, Pages 1903-1904

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btw098

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Funding

  1. Deutsche Forschungsgemeinschaft (DFG) [FOR 1078, ME 3134/3-2]
  2. SPP Priority Programme 1590 'Probabilistic Structures in Evolution'

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A Summary: Simulation programs based on the coalescent efficiently generate genetic data according to a given model of evolution. We present coala, an R package for calling coalescent simulators with a unified syntax. It can execute simulations with several programs, calculate additional summary statistics and combine multiple simulations to create biologically more realistic data.

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