Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 64, Issue 1, Pages -Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01281-19
Keywords
bacteriophages; urinary tract infection; Klebsiella pneumoniae; extended spectrum beta-lactamase; renal transplant
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We report a case of a 58-year-old renal transplant patient who developed a recurrent urinary tract infection with an extended-spectrum beta-lactamase (ESBL)-positive Klebsiella pneumoniae strain in the first month posttransplant. Even though it tested susceptible to carbapenems and despite repeated meropenem treatment, his infection recurred. The infection eventually evolved into epididymitis that was successfully treated with meropenem and bacteriophages. This case demonstrates the difficulty of treating relapsing ESBL-positive Gram-negative infections in renal transplant patients.
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