Journal
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 15, 2020
Volume 15, Issue -, Pages 315-343Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev-pathmechdis-012419-032640
Keywords
malaria; Plasmodium falciparum; pathogenesis; cerebral malaria; host-pathogen interactions
Categories
Funding
- Wellcome Trust
- European Research Council
- Royal Society
Ask authors/readers for more resources
Malaria remains a major public health threat in tropical and subtropical regions across the world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 deaths per year, predominantly in young children in sub-Saharan Africa. Therefore, it is imperative to understand why a subset of infected individuals develop severe syndromes and some of them die and what differentiates these cases from the majority that recovers. Here, we discuss progress made during the past decade in our understanding of malaria pathogenesis, focusing on the major human parasite Plasmodium falciparum.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available