Journal
AMERICAN JOURNAL OF TRANSPLANTATION
Volume 20, Issue 2, Pages 348-354Publisher
WILEY
DOI: 10.1111/ajt.15680
Keywords
immunosuppression; immune modulation; stem cells; tolerance; chimerism; tolerance; clinical; tolerance; mechanisms; translational research; science
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In 2017, the American Society of Transplantation (AST) launched the Outstanding Questions in Transplantation Research forum to stimulate a community-wide discussion of how the field is evolving and to help identify areas where a better dialogue between clinicians and researchers could result in great advancements. Tolerance emerged as a topic of great interest to the AST community. This minireview provides an overview of clinical transplantation tolerance. Historical background followed by a review of the current status of attempts to establish tolerance in the clinic, highlighting the dynamic online discussion surrounding this important topic from the AST Transplantation Research forum, is provided.
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