Journal
ADVANCES IN THERAPY
Volume 37, Issue 1, Pages 381-389Publisher
SPRINGER
DOI: 10.1007/s12325-019-01154-7
Keywords
Blood pressure variability; Essential hypertension; Homocysteine; Left ventricular hypertrophy; Relationship
Funding
- Yulin Science and Technology Research Project [161034]
- Guangxi Science and Technology Plan Project [1598011-2]
- PRIME China Post-Single Group Study (XP China SAS) [12-396]
Ask authors/readers for more resources
Introduction This study aimed to investigate the relationship between homocysteine (Hcy) and blood pressure variability (BPV) and the relationship between Hcy and left ventricular hypertrophy (LVH) in 102 patients with essential hypertension. Methods The 102 patients were divided into the Hcy < 10 mu mol/L group (n = 47) and the Hcy >= 10 mu mol/L group (n = 55) according to Hcy concentration. The differences between Hcy and BPV and Hcy and LVH were compared between the two groups. Finally, the correlations between Hcy and BPV and between Hcy and LVH were analyzed. Results The results showed that there were significant differences between Hcy and BPV and between Hcy and LVH in the two groups. Hcy correlated positively with the coefficient of variation in nighttime diastolic blood pressure and night systolic blood pressure standard deviation (nDBPSD), with correlation coefficients of 0.331 and 0.303 (P < 0.001). At the same time, Hcy correlated positively with interventricular septal thickness and left ventricular posterior wall thickness, which were indicators of LVH, with correlation coefficients of 0.350 and 0.352 (P < 0.001). Conclusions There was a correlation between Hcy and BPV and between Hcy and LVH. Attention should also be paid to blood Hcy and BPV for patients with essential hypertension.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available